The Effect of RF Turbinoplasty in Polypoid Change of Middle Turbinates

Status Active, not recruiting

Clinical Trial Summary

The aim of this study is to evaluate the effect of middle turbinate Radio Frequency (RF) turbinoplasty with middle turbinate resection and medialization

Clinical Trial Description

The management of middle turbinate in treatment of nasal polyposis is still an interesting debatable topic. The surgical access and its possible role in pathophysiology of sinusitis are two important points about its treatment. On the one hand, middle turbinate resection can improve surgical access and possibly reduce the nasal polyposis recurrence. On the other hand, there are some reports of anosmia, empty nose syndrome, synechia, and difficulties in revision surgery. Also, synechia, lateralization, and possibly recurrence can be the possible outcome after middle turbinate preservation.

Among different modalities, radiofrequency (RF) gradually increase its popularity as surgical tools, which can treat mucosal hypertrophy without any tissue removal. Inferior turbinate is a famous place for its usage, especially for decreasing of the nasal obstruction. Also, some authors have showed its effect on refractory allergic rhinitis, which is not only related to reducing of nasal obstruction, but also it is related to changing of the allergic mediators. [5, 6] Comparing to other treatments for turbinates is sparing its overlaid mucosa, which can reduce the possible future morbidities.

Probably considering of the above mention points, RF has a possible impact on the polypoid changes of middle turbinates and possibly does not have the same deleterious effect of the resection on cilia of mucosal layer. Therefore, we performed a randomized clinical trial to compare its outcome with two famous methods of the middle turbinate management: partial resection and medialization. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01906697
Study type	Interventional
Source	Tehran University of Medical Sciences
Contact
Status	Active, not recruiting
Phase	Phase 3
Start date	May 2011
Completion date	October 2013

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT03584178` - The Long-Term Safety of Budesonide for Patients With Chronic Rhinosinusitis	N/A
Completed	`NCT06016335` - MRI-based Synthetic CT Images of the Head and Neck	N/A
Active, not recruiting	`NCT02278484` - Sinus Balloon Dilation in Pediatric Patients	N/A
Withdrawn	`NCT02071667` - Association of Periostin Levels and Chronic Sinusitis	N/A
Completed	`NCT01420471` - Medicated Punctured-Glove-Finger Spacer Study	Phase 4
Completed	`NCT01118312` - Study of Asthma and Nasal Steroids	Phase 4
Completed	`NCT00645762` - Balloon REmodeling Antrostomy THErapy Study	Phase 2
Completed	`NCT01685229` - Medical Therapy Versus Balloon Sinus Dilation for Patients With Chronic Rhinosinusitis
Active, not recruiting	`NCT03943121` - The Effects of Steroid-eluting Stent Implant for the Treatment of Eosinophilic Chronic Rhinosinusitis With Nasal Polyps	N/A
Withdrawn	`NCT02900794` - Gold Laser Vs. Micro-Debriders for Functional Endoscopic Sinus Surgery	N/A
Terminated	`NCT02630472` - Topical Irrigation Therapy for CRS	Phase 1/Phase 2
Completed	`NCT01442740` - 15-Degree Tilt, Head Up, Feet Down Body Position for Sinus Surgery Patients	N/A
Completed	`NCT01001039` - Validation of the Facial and Cephalic Pain Inventory	N/A
Completed	`NCT01033799` - Effect of the Consumption of a Fermented Milk on Common Infections in Shift-workers	N/A
Completed	`NCT00242437` - Hemostatic Matrix in Endoscopic Sinus Surgery	Phase 4
Completed	`NCT00335309` - Maxillary Sinus Irrigation in the Management of Chronic Rhinosinusitis	N/A
Completed	`NCT00236522` - A Comparison of the Safety and Efficacy of Two Different Regimens of Levofloxacin in the Treatment of Acute Bacterial Sinusitis(Sinus Infection) in Adults.	Phase 3
Completed	`NCT01717274` - Hot Saline Irrigation Study	N/A
Completed	`NCT01166945` - Short (5 Days) Versus Long (14 Days) Duration of Antimicrobial Therapy for Acute Bacterial Sinusitis in Children	N/A
Not yet recruiting	`NCT00545961` - Middle Meatal Bacteriology During Acute Respiratory Infection in Children	Phase 4