Nasal Disease Clinical Trial
Official title:
Chia Yi Chang Gung Memorial Hospital
This study investigate the nasal irrigation with Traditional herbal medicine extract-saline isotonic solution in the treatment of chronic rhinitis and sinusitis. Half of participants will receive Traditional herbal medicine extract-saline isotonic solution nasal irrigation, while the other half will receive saline alone nasal irrigation.
In the program, the investigators plan to investigate a clinical triad to research the
outcomes of nasal irrigation with Traditional herbal medicine extract-saline isotonic
solution for treatment of chronic rhinitis and sinusitis. The aims of this study are listed
below:
Aim 1: evaluating the outcomes and quality of life of nasal irrigation with Traditional
herbal medicine extract-saline isotonic solution to treat enrolled patients with chronic
rhinitis or sinusitis. The investigators use modern devices to evaluate the autonomic nerve,
meridian energy and pulse. The questionnaires of quality of life and symptoms will be
recorded. Nasal irrigation with saline alone will be conducted during the clinical triad to
compare the effectiveness and quality of life with Traditional herbal medicine extract.
Aim 2: analyzing the changes of bacteria culture in nasal discharge collected during the
clinical triad before and after nasal irrigation for investigating the microenvironment of
Traditional herbal medicine extract-saline isotonic solution.
According to the research, the investigators will realize the improvement of using
Traditional herbal medicine extract-saline isotonic solution for nasal irrigation to treat
sino-nasal diseases, by investigating the changes of quality of life and microenvironment of
nasal cavity. The nasopharyngoscopic examination, autonomic nerve, meridian energy and pulse
were record to compare the effectiveness of Traditional herbal medicine extract-saline
isotonic solution with nasal irrigation with saline alone.
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