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Understanding How Opioids Affect the Experiential and Neural Signatures of Social Experiences

Placebo Clinical Trial

Official title:
Understanding How Opioids Affect the Experiential and Neural Signatures of Social Experiences

Clinical Trial Summary

The study is a randomized, placebo-controlled design with the opioid antagonist, oral naltrexone. Following random assignment, participants will take 50mg of naltrexone or placebo once a day for 7 days. On days 1 - 7, participants complete reports of their feelings of social connection and mood in order to assess more naturalistic feelings in response to opportunities for social connection outside of the laboratory setting. Additionally, at the end of each day, they complete a physical symptoms questionnaire. On the 7th day, participants will come to the SDSU MRI scanning facility to complete tasks designed to elicit feelings of social connection in the fMRI scanner. After the scan, feelings in response to the scanner tasks will be collected.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05007561
Study type Interventional
Source San Diego State University
Contact Tristen Inagaki, PhD
Phone 6195941058
Email tinagaki@sdsu.edu
Status Recruiting
Phase Early Phase 1
Start date November 16, 2021
Completion date July 2026
View Details
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