Nail Psoriasis Clinical Trial
Official title:
Effect of Methotrexate in the Treatment of Distal Interphalangeal Joint Extensor Tendon Enthesopathy in Patients With Nail Psoriasis
Verified date | November 2018 |
Source | University of Warmia and Mazury |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
The primary aim of the study is to assess the effect of methotrexate on the development of distal interphalangeal joint extensor tendon enthesopathy.
Status | Completed |
Enrollment | 32 |
Est. completion date | September 30, 2018 |
Est. primary completion date | September 30, 2018 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 34 Years to 57 Years |
Eligibility |
Inclusion Criteria: - Patients with psoriatic changes in nails treated at the Rheumatological Clinic in Olsztyn and the Clinic of Dermatology, Sexually Transmitted Diseases and Clinical Immunology of the University of Warmia and Mazury in Olsztyn, in whom a US examination revealed DIP joint extensor tendon enthesopathy Exclusion Criteria: - Patients diagnosed with osteoarthritis of hands, those who work hard physically and those with changes in nails other than caused by psoriasis |
Country | Name | City | State |
---|---|---|---|
Poland | University of Warmia and Mazury | Olsztyn | Warminsko-mazurskie |
Lead Sponsor | Collaborator |
---|---|
Ryszard Górecki |
Poland,
Krajewska-Wlodarczyk M, Owczarczyk-Saczonek A, Placek W, Wojtkiewicz M, Wiktorowicz A, Wojtkiewicz J. Ultrasound Assessment of Changes in Nails in Psoriasis and Psoriatic Arthritis. Biomed Res Int. 2018 Sep 9;2018:8251097. doi: 10.1155/2018/8251097. eCollection 2018. — View Citation
McGonagle D, Tan AL, Benjamin M. The nail as a musculoskeletal appendage--implications for an improved understanding of the link between psoriasis and arthritis. Dermatology. 2009;218(2):97-102. doi: 10.1159/000182250. Epub 2008 Dec 6. Review. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Effect of Methotrexate on Distal Interphalangeal Joint Extensor Tendon Enthesopathy | Ultrasonographic assessment of the effect of methotrexate on the development of distal interphalangeal joint extensor tendon enthesopathy in patients with nail psoriasis. | 6 months | |
Secondary | Effect of Methotrexate on Morphological Changes in Psoriatic Nails | Ultrasonographic assessment of the effect of methotrexate on morphological changes in psoriatic nails | 6 months |
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