Clinical Trials Logo
  1. Home
  2. Nail Psoriasis
  3. NCT01445886

Comparison of Indigo Naturalis Oil Extract and Calcipotriol Solution in Treating Psoriasis

Nail Psoriasis Clinical Trial

Official title:
Evaluation of the Efficacy and Safety of Indigo Naturalis Oil Extract and Calcipotriol Solution in Patients With Nail Psoriasis

Clinical Trial Summary

The purpose of this study is to compare the efficacy and safety of indigo naturalis oil extract and calcipotriol solution in the treatment of psoriatic nails, to show that indigo naturalis oil extract may be a good choice for treating nail psoriasis, and potentially an effective alternative for those who do not respond well to traditional therapy.

Clinical Trial Description

In the literature, the efficacy of traditional Chinese medicine in treating nail psoriasis is rarely reported. Recently, the investigators developed a new product, indigo naturalis oil extract, which worked well in nail disease. In our randomized, observer-blind, vehicle-controlled trial showed that indigo naturalis oil extract is effective and safe in treating nail psoriasis. This study aims to compare the efficacy and safety of indigo naturalis oil extract with calcipotriol solution in patients with nail psoriasis using controlled, bilateral comparison

The investigators will enroll 33 patients with nail psoriasis from the ambulatory department of Chang Gung Memorial Hospital. Indigo naturalis oil extract will be consistently applied on either the left or right affected nail folds, while calcipotriol will be applied on the opposite side, both twice daily for 24 weeks, allowing intra-patient comparison. The nails will be assessed by two dermatologists before treatment and at week 2, 4, 8, 12, 16, 20, 24. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01445886
Study type Interventional
Source Chang Gung Memorial Hospital
Contact
Status Completed
Phase Phase 2/Phase 3
Start date January 2011
Completion date March 2013
View Details
See also
  Status Clinical Trial Phase
Not yet recruiting NCT03209388 - Study of the Efficacy and Safety of Topical P-3073 in the Treatment of Mild to Moderate Psoriatic Fingernail/s Phase 3
Completed NCT00999687 - Evaluation of the Efficacy and Safety of Indigo Naturalis Oil Extract on Psoriatic Nails Phase 2/Phase 3
Completed NCT00581100 - Effects of Etanercept on Nail Psoriasis and Plaque Psoriasis Phase 4
Completed NCT04580537 - Assessing the Efficacy of Image-guided Laser-assisted Enstilar® Delivery for Treatment of Psoriatic Nails Phase 2
Not yet recruiting NCT03263624 - Efficacy of Combined Fractional Carbon Dioxide Laser and Topical Tazarotene in the Treatment of Psoriatic Nail Disease Phase 4
Completed NCT02606760 - Study to Evaluate the Efficacy and Safety of P-3073 Nail Solution in the Treatment of Nails Affected by Psoriasis Phase 3
Completed NCT04227288 - A Study Evaluating the Efficacy and Tolerability of Enstilar Foam in Patients With Nail Psoriasis Phase 4
Withdrawn NCT03079973 - Study to Evaluate the Efficacy and Safety of P-3073 Nail Solution in the Treatment of Mild to Moderate Psoriatic Fingernail/s Phase 3
Completed NCT04380597 - Observational Study in Patients With Nail Psoriasis Treated With Enstilar® to Assess the Severity Change and the Quality of Life
Completed NCT03991936 - Benefit of Placebo and Different Concentrations of Triamcinolone Acetonide in Nail Psoriasis Phase 4
Recruiting NCT05124080 - An Investigator Initiated Open Label Study Evaluating the Efficacy and Tolerability of Oral Deucravacitinib for the Treatment of Nail Psoriasis Early Phase 1
Completed NCT03757364 - Methotrexate in the Treatment of Distal Interphalangeal Joint Extensor Tendon Enthesopathy in Nail Psoriasis
Completed NCT02168933 - 308nm Excimer Laser for Treatment of Fingernail Psoriasis N/A
Completed NCT02016482 - A Study to Evaluate the Safety and Efficacy of Adalimumab in Subjects With Chronic Plaque Psoriasis and Nail Psoriasis Phase 3
Not yet recruiting NCT05695833 - Nd:YAG Laser and Radiofrequency in Treatment of Fingernail Psoriasis N/A
Completed NCT03616561 - Quality of Life and Ultrasonographic Assessment of Nail Psoriasis After Treatment With Apremilast (JUST Study)
Completed NCT02235480 - Efficacy and Safety of Tazarotene Gel in Nail Psoriasis Phase 2
Not yet recruiting NCT06150794 - Methotrexate Alone vs Combination With Excimer Light in Nail Psoriasis N/A
Completed NCT03946826 - A Clinical Observation on the Efficacy and Safety of Pulsed Dye Laser (PDL) in the Treatment of Nail Psoriasis N/A
Active, not recruiting NCT05072886 - Study of Efficacy and Safety of Investigational Treatment in Patients With Nail Psoriasis Phase 1