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Myopic Progression clinical trials

View clinical trials related to Myopic Progression.

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NCT ID: NCT02643875 Completed - Myopic Progression Clinical Trials

Investigation of the Effect of Short-term Orthokeratology With Increased Compression Factor on Ocular Parameters

Start date: February 26, 2016
Phase: N/A
Study type: Interventional

Orthokeratology (ortho-k) is a clinical technique that uses reverse geometry rigid gas permeable contact lens exerting positive pressure on the central cornea to temporary reduce refractive error. Researchers have shown that this treatment is effective for myopia control in low to high myopes, with and without astigmatism. Most designs of ortho-k lenses in the market are fitted based on the Jessen formula. The compression factor was introduced to compensate for the regression of the ortho-k effect during the no lens-wear period, so that the wearer can obtain clear distance vision throughout the day and most lens designs use a compression factor of 0.50-0.75 D. However, in a retrospective study (mixed brands of ortho-k lenses), it showed that most patients did not achieve an over-correction of 0.75 D. In order to achieve an over-correction of 0.75 D, an extra flattening power of about 1.50 D instead of 0.75 D should be be targeted. The increased compression factor is expected to increase the target reduction and it may play a role in myopic control and providing a higher successful rate in fitting ortho-k lenses.

NCT ID: NCT02643342 Completed - Myopic Progression Clinical Trials

A 2-year Longitudinal Study on the Structural and Optical Effects of Orthokeratology Treatment on Eye

Start date: June 18, 2016
Phase: N/A
Study type: Interventional

This is a two-year longitudinal study investigating the optical and structural effects of increased compression factor of orthokeratology lens on eyes and the corresponding effect on change in choroidal thickness and therefore myopic control.