Myopia Clinical Trial
Official title:
Toric Orthokeratology for Slowing Eye Elongation in Astigmatic Children
The aims of this study are to investigate the effects of ortho-k for astigmatic and myopic reduction and myopic control in children, and the long term effects on corneal curvatures and biomechanics.
Ortho-k has been shown to be effective in correcting low myopia but relatively ineffective
for astigmatism, using spherical reverse geometry lens designs. Toric ortho-k lenses have
been introduced in recent years but the efficacy for astigmatic reduction and for myopic
control in children have not been confirmed. The mechanism of myopic reduction in ortho-k
cannot be fully explained by changes to the anterior corneal curvatures. It is therefore
possible that other corneal parameters such as posterior corneal curvature and corneal
biomechanics may contribute to the mechanism.
The current study aims at investigating the efficacy of toric ortho-k lenses for correcting
myopic astigmatism and for retarding myopic progression in children compared to children
wearing single-vision spectacles. Long term changes to other corneal parameters such as
posterior cornea curvatures, topographical corneal thickness, corneal hysteresis, corneal
resistance factor, with and without ortho-k lens wear will also be investigated.
;
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment
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