Myopia Clinical Trial
Official title:
Efficacy of Combining Intravitreal Bevacizumab With Photodynamic Therapy Using Reduced Light Fluence Rate in Choroidal Neovascularization Secondary to Pathologic Myopia.
The purpose of this study is to report the treatment effect and safety of combined intravitreal bevacizumab (IVB) and photodynamic therapy (PDT) with verteporfin using a reduced (RF) light fluence rate, in choroidal neovascularization (CNV) secondary to pathologic myopia.
In this retrospective interventional case series, 16 patients with myopic CNV were included.
All patients were treated with 1.25 mg of intravitreal bevacizumab followed by RF-PDT (25
J/cm²), 2 days later. All patients were previously treated with IVB monotherapy and active
leaking of CNV occurred 90 to 120 days after the treatment.
Best-corrected visual acuity (BCVA-ETDRS), foveal thickness (FT) on optical coherence
tomography (OCT), and fluorescein and indocyanine green angiographic (FA; ICG) findings were
recorded. Follow-up evaluations were carried out for 12 months.
;
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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