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Myopia, Degenerative clinical trials

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NCT ID: NCT05597163 Not yet recruiting - Myopia, Progressive Clinical Trials

Efficacy and Safety of Low-concentration Atropine for Myopia Control in Chinese Children and Adolescents

LAMC
Start date: January 15, 2023
Phase: N/A
Study type: Interventional

To investigate the efficacy and safety of three low-concentration atropine sulfate eye drops (0.01%, 0.025% and 0.05%) in controlling the progression of myopia in Chinese children and adolescents through a two-year clinical trial.

NCT ID: NCT05562336 Not yet recruiting - Clinical trials for Choroidal Neovascular Membrane In Wet Age Related Macular Degeneration And In Pathological Myopia

Optical Coherence Tomography Angiography Criteria Of The Choroidal Neovascular Membrane In Wet Age Related Macular Degeneration And In Pathological Myopia (Comparative Study).

Start date: October 2022
Phase:
Study type: Observational

This study aims to compare choroidal neo-vascular membrane criteria in cases of age-related macular degeneration and cases of pathological myopia.

NCT ID: NCT05373693 Active, not recruiting - Myopia, Progressive Clinical Trials

Myopia-control Efficacy by Peripheral Defocus Lens (PDL)

Start date: July 1, 2019
Phase: N/A
Study type: Interventional

The proposed study below aims to assess the effect of customized Bestivue PDL lenses on retinal image quality and myopia control. A total of 160 subjected would be enrolled in and randomized to allcoate into four groups. Visual acuity and image blur at various gaze directions and eccentricities on children fitted with +2 to 4 D power and single vision lenses would be measured to assess the short term effect of PDL lens. Axial length and cycloplegic objective refractive error would be measured to assess the Myopia-control Efficacy.

NCT ID: NCT05372991 Completed - Myopia, Progressive Clinical Trials

Safety, Tolerability and Pharmacodynamics Evaluation of CBT-009 Eye Drop

Start date: July 20, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

This is a Two-Stage Phase 1/2 study to evaluate the safety, tolerability and pharmacodynamics of CBT-009 eye drop in healthy volunteers. CBT-009 has the active ingredient of atropine, which at low doses, has shown to be effective in slowing down myopic deterioration. Current atropine products are prone to degradation once the container is open to the air. ADS Pharmaceutical has developed a novel atropine formulation.

NCT ID: NCT05331378 Active, not recruiting - Myopia Clinical Trials

Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression

Start date: April 25, 2022
Phase: N/A
Study type: Interventional

This is a monocenter, randomized, controlled, parallel-group, double-masked clinical trial to evaluate the effectiveness of test lens in slowing myopia progression with respect to axial length elongation at baseline compared to a single vision spectacle lens (control). A total of 80 children will be recruited where 40 subjects will be allocated either to wear test lenses (group 1) or control lenses (group 2) for 1 year through randomization.

NCT ID: NCT05300321 Completed - Myopia, Progressive Clinical Trials

DIMS-myopia Progression ADN Axial Length Growth

Start date: June 1, 2019
Phase: N/A
Study type: Interventional

To confirm the efficacy of DIMS lenses in controlling myopia progression, we planned a prospective randomized controlled clinical study.

NCT ID: NCT05159765 Recruiting - Myopia Clinical Trials

Progressive Myopia Treatment Evaluation for NaturalVue Multifocal Contact Lens Trial

PROTECT
Start date: January 22, 2022
Phase: N/A
Study type: Interventional

This is a multi-center, randomized, double-masked clinical trial. All study devices are market approved/cleared in the localities where the study is conducted. Subjects will be randomly assigned to wear NaturalVue Sphere single vision contact lenses (SVCL) or NaturalVue Multifocal (NVMF) soft contact lenses for a total of three years.

NCT ID: NCT05007626 Completed - Myopia, Progressive Clinical Trials

Near Horizontal Heterophoria in Chinese Children

Start date: January 29, 2017
Phase:
Study type: Observational

This study aimed to assess the association of refraction and axial length with near-horizontal heterophoria in a large population-based study of school-aged Chinese children. The study makes a significant contribution to better know the etiology of myopia progression and ocular axial length development. Further, this study will be of interest to the readership of your journal because its noteworthy finding and which could contribute to guide recommendations for targeted interventions to slow myopia progression.

NCT ID: NCT04806763 Completed - Children, Only Clinical Trials

Myopia Control With Orthokeratology Contact Lenses in Spain

MCOS
Start date: March 1, 2007
Phase: N/A
Study type: Interventional

The purpose of this prospective study is to assess the efficacy, safety and patient-reported outcomes of the Menicon Z Night orthokeratolgy contact lens for reducing myopia progression in children.

NCT ID: NCT04806711 Completed - Children, Only Clinical Trials

Eleven Years of Menicon Z Night Contact Lens Wear in Reducing Myopia Progression in Children

MCOS11
Start date: March 1, 2007
Phase: N/A
Study type: Interventional

To compare axial length growth of white European myopic children wearing Menicon Z Night orthokeratology contact lenses to a control group of distance, single-vision glasses and contact lenses over an 11-year period.