Clinical Trials Logo

Clinical Trial Summary

Aim and objectives; To compare the efficacy of preoperative administration of dinoprostone 20 mg versus 400 ug misoprostol vaginally in decreasing the amount of bleeding during abdominal myomectomy


Clinical Trial Description

Background; Myomectomy is a curative interventional option for many kinds of uterine fibroids, but considerable intraoperative haemorrhage and the necessities for transfusions of blood are still the main challenge for abdomen myomectomy. Aim and objectives; To compare the efficacy of preoperative administration of dinoprostone 20 mg versus 400 ug misoprostol vaginally in decreasing the amount of bleeding during abdominal myomectomy Subjects and methods; This was a prospective randomized double-blind controlled study that included 90 patients complaining of uterine myoma and indicated for myomectomy selected from the outpatient clinic at Beni-suef university hospital ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05761418
Study type Interventional
Source Beni-Suef University
Contact
Status Completed
Phase Phase 3
Start date March 1, 2018
Completion date February 20, 2023

See also
  Status Clinical Trial Phase
Recruiting NCT04519593 - ABSOLUTELY: A Temporary Uterine Blood Supply Occlusion for Laparoscopic Myomectomy in Patients With UTErine LeiomYoma N/A
Active, not recruiting NCT06114758 - Comparison Effectiveness of Rectal Misoprostol & Intravenous Tranexamic Acid Reducing Hemorrhage in Myomectomy
Not yet recruiting NCT05967936 - Paracervical Block Versus Transcervical Block in Outpatient Procedural Hysteroscopy N/A
Not yet recruiting NCT05932082 - The Impact of Myomectomy on IVF Outcomes N/A
Recruiting NCT04748978 - OPPIuM Technique and Myolysis With Diode Laser Dwls N/A
Recruiting NCT05271981 - Fertility After Uterine Artery Embolization
Completed NCT05025410 - Remimazolam and Remifentanil Without Neuromuscular Blocking Agent
Recruiting NCT03483142 - the Effect of Misoprostol on Intra-operative Blood Loss During Myomectomy Operation Phase 3
Completed NCT03533907 - Pregnancy Outcomes in Infertile Patients After Treatment With Ulipristal Acetate.
Completed NCT05811286 - The Use of a Morcellator in Operative Hysteroscopy for Benign Intracavitary Lesions: a Feasibility Study N/A
Not yet recruiting NCT03570879 - Laparoscopic Myomectomy With Morcellation or Transvaginal Extraction of Surgical Specimens.
Not yet recruiting NCT04364581 - Endometrial Preparation by Short Course of Letrozole Before Hysteroscopic Removal of Endocavitary Lesions Phase 4
Recruiting NCT06067971 - Evaluation of the Feasibility of Using Augmented Reality in Laparoscopic Surgery, by a Clinical Study During Gynecological Laparoscopic Surgical Procedures. (ENDORA2) N/A
Recruiting NCT04990076 - Ultrasound Evaluation of the Myometrium Using the MUSA Terminology Comparison With Histology
Recruiting NCT06325501 - Misoprostol Versus Oxytocin Infusion On Reducing Blood Loss During Abdominal Myomectomy Phase 3
Recruiting NCT04311073 - Prophylactic Tranexamic Acid During Minimally Invasive Myomectomies Phase 3
Active, not recruiting NCT05930769 - Retrospective Study on the Evaluation of the Impact of Augmented Reality Usage in Gynecological Laparoscopy on Patients Operated Between 2017 and 2021 (ImpactRA)
Recruiting NCT03550703 - Open Label Immunotherapy of Myoma Phase 2
Completed NCT04482959 - Intraoperative Carbetocin to Decrease Blood Loss During Hysteroscopic Myomectomy Phase 4
Not yet recruiting NCT04030273 - Prevalence of Intrauterine Adhesions After Abdominal Myomectomy