Myofascial Pain Clinical Trial
Official title:
Evaluation of Mitochondrial Function in Chronic Myofascial Trigger Points - A Prospective Cohort Pilot Study Using High-resolution Respirometry
This pilot study established a minimally invasive biopsy technique to obtain high-quality MTrP tissue samples to evaluate mitochondrial function via high-resolution respirometry.
Myofascial trigger points (MTrPs) are hyperirritable areas in the fascia of the affected muscle, possibly related to mitochondrial impairment. They can result in pain and hypoxic areas within the muscle. This pilot study established a minimally invasive biopsy technique to obtain high-quality MTrP tissue samples to evaluate mitochondrial function via high-resolution respirometry. Secondary objectives included the safety of the biopsy procedure assessed via clinical wound healing (number of patients with signs for local infection and inflammation). For this purpose, twenty healthy males participated in this study, 10 with a diagnosis of myofascial pain in the musculus (m.) trapezius MTrP (TTP group) and 10 with a diagnosis of myofascial pain in the m. gluteus medius (GTP group). The affected muscle was biopsied followed by a biopsy from the vastus lateralis to be used as a control. Measurements of oxygen consumption were carried out using high-resolution respirometry. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04157426 -
Percutaneous Electrolysis Versus Dry Needling in Levator Scapulae
|
N/A | |
Enrolling by invitation |
NCT06029413 -
Myo vs. Myofascial Injection for Myofascial Trigger Points
|
N/A | |
Not yet recruiting |
NCT05637047 -
Pulsed Radiofrequency vs Dry Needling in Myofascial Pain
|
N/A | |
Completed |
NCT04057781 -
Pain and Neck Dysfunction Following Dry Needling With and Without Intramuscular Electrical Stimulus.
|
N/A | |
Recruiting |
NCT06036524 -
Multi-modal Imaging of Myofascial Pain
|
N/A | |
Completed |
NCT04897581 -
BBTI vs PSR in Musculoskeletal Orofacial Pain Adults
|
N/A | |
Completed |
NCT03398486 -
The Effectiveness of Kinesiotaping and Inactivation of Trigger Points in Chronic Myofascial Pain of TMD
|
N/A | |
Recruiting |
NCT05928884 -
Ultrasound Imaging for Myofascial Pain
|
||
Completed |
NCT04790071 -
Dry Needling Treatment in Hemiplegic Shoulder Pain
|
N/A | |
Completed |
NCT05365932 -
Evaluation of an Intra Auricular Device as a Treatment for Painful Temporo-Mandibular Disorders
|
N/A | |
Completed |
NCT04628286 -
Myofascial Induction Effects on Stabilometry Versus Sham Laser
|
N/A | |
Completed |
NCT04628299 -
Effects of the Myofascial Induction Technique Versus a Control Laser
|
N/A | |
Completed |
NCT04884152 -
Telerehabilitation in Individuals Temporomandibular Dysfunction With Bruxism
|
N/A | |
Completed |
NCT01850420 -
A Study of IMC-1 In Patients With Fibromyalgia
|
Phase 2 | |
Terminated |
NCT03028012 -
TPI Medication Comparison - Ketorolac, Lidocaine, or Dexamethasone
|
Phase 4 | |
Completed |
NCT04929171 -
Myofascial Pain and Central Sensitization
|
||
Completed |
NCT04040309 -
PRGF Effectiveness for Myofascial Pain Treatment in Masticatory Muscles
|
Phase 4 | |
Completed |
NCT03651141 -
The Effects of Soft Tissue Therapy and Exercise on Hamstring Tightness
|
N/A | |
Recruiting |
NCT03885791 -
Randomized Controlled Trial of Vaginal Cryotherapy for Pelvic Floor Myofascial Pain
|
N/A | |
Completed |
NCT02389140 -
Blood Flow Within Active Myofascial Trigger Points Following Massage
|
N/A |