Clinical Trials Logo
  1. Home
  2. Myocarditis
  3. NCT04844151

Acute Myocarditis Registry With Prognostic, Histologic, Immunologic, Biological, Imaging and Clinical Assessment — AMPHIBIA  

Myocarditis Clinical Trial

Official title:
Acute Myocarditis Registry With Prognostic, Histologic, Immunologic, Biological, Imaging and Clinical Assessment

Clinical Trial Summary

The AMPHIBIA study is an observational ambispective and prospective cohort that aim to describe the histologic, immunologic, biological, imaging, genetic and clinical characteristics of the patients hospitalized for an acute myocarditis and to evaluate their association with prognosis.

Clinical Trial Description

Acute myocarditis is an inflammatory disease of the heart muscle. Its clinical presentation and its etiologies are multiple and make it a complex disease to treat. Its course also varies, ranging from complete clinical recovery to recurrence of ventricular arrhythmia or progression to chronic dilated heart disease, while being difficult to predict. The long-term prognosis is poorly understood. Consecutive patients hospitalized in a tertiary university referral center cohort from 2006 to 2041 for an acute myocarditis will be ambispectively or prospectively analyzed. This project will establish a registry including up to 400 patients in the ambispective analysis cohort from 2006 to 2021 and 1000 patients in the prospective analysis cohort during a 20 years inclusion period. The aim of the study is to describe the characteristics of patients hospitalized for an acute myocarditis and to evaluate their association wih the long term (until 20 years) prognosis. Features of interest will include : - Clinical - Biological - Etiological - Echocardiographic - Cardiac magnetic resonance imaging - Genetics (for the prospective cohort) - Anatomopathological The collection of clinical, biological and radiological data will represent an unique source allowing research teams in the coming years to access the data necessary to answer various specific questions (pathophysiological, diagnostic, prognostic) relevant to the state of knowledge on this pathology. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04844151
Study type Observational [Patient Registry]
Source Assistance Publique - Hôpitaux de Paris
Contact Mathieu Kerneis, MD
Phone +33142163001
Email mathieu.kerneis@aphp.fr
Status Recruiting
Phase
Start date January 23, 2022
Completion date May 1, 2041
View Details
See also
  Status Clinical Trial Phase
Not yet recruiting NCT05911386 - Multiparametric Echocardiography and Cardiac Biomarkers in Pediatric Inflammatory Heart Diseases
Not yet recruiting NCT04085718 - FDG-PET/CT Images Comparing to MRI and Endomyocardial Biopsy in Myocarditis
Enrolling by invitation NCT05610423 - Covid-19 Vaccine Associated Myocarditis and Pericarditis in Norway
Active, not recruiting NCT05195645 - AbataCept for the Treatment of Immune-cHeckpoint Inhibitors Induced mYocarditiS Phase 2
Recruiting NCT05184114 - Clinical Significance of Subclinical Myocardial Involvement in Recovered COVID-19 Patients Using Cardiovascular Magnetic Resonance N/A
Recruiting NCT04612296 - The Heart Hive - Cardiomyopathy Study
Recruiting NCT04673409 - CMR Imaging of Autoimmune Diseases
Recruiting NCT05295290 - A Study to Learn About The COVID-19 (Study) Vaccine (Called COMIRNATY) in People That Are Less Than 21 Years Old. Phase 4
Completed NCT03777839 - PET-FDG in Myocarditis
Not yet recruiting NCT05125965 - Contribution of Cardiac MRI in the Early Diagnosis of Myocarditis Induced by Immunotherapy N/A
Active, not recruiting NCT04444128 - IMPRoving Cardiovascular RiSk Stratification Using T1 Mapping in General populatION
Recruiting NCT06158698 - CMP-MYTHiC Trial and Registry - CardioMyoPathy With MYocarditis THerapy With Colchicine Phase 3
Recruiting NCT05282498 - Pathophysiologic Mechanism for MYOcarditis in COVID19 VAccinations ("MYOVAx" Study)
Recruiting NCT05288426 - Myocarditis Post Vaccination or Multi System Inflammatory Syndrome
Recruiting NCT03801681 - ARrhythmias in MYocarditis
Recruiting NCT06116084 - Randomized Controlled Study Evaluating the Efficacy of Hypnosis in Nuclear Medicine N/A
Completed NCT04413071 - Cardiac COVID-19 Health Care Workers
Recruiting NCT05414162 - Multiparametric Cardiac MRI in Patients Under CAR T-cell Therapy
Completed NCT02299856 - Cardiac Magnetic Resonance in Acute Myocarditis N/A
Recruiting NCT01089036 - Oxidant-antioxidant Activity, Free Radicle Activity, Immune Response and Biomarkers in Extracorporeal Membrane Oxygenation (ECMO) Patients N/A