Clinical Trials Logo

Clinical Trial Summary

Myocardial stunning during chronic intermittent hemodialysis is a well-described phenomenon. Little case series of patients presenting myocardial stunning during renal replacement therapy for acute kidney injury in critically ill patients are reported, with intermittent hemodialysis and continuous renal replacement therapy. However, the small sample sizes and the absence of a control arm limit their interpretation, mainly whether the myocardial stunning may be related to cardiac loading conditions variations and whether it may impact the hemodynamic. The investigator hypothesize that myocardial stunning induced by renal replacement therapy is frequent, independent from cardiac loading conditions and associated with peripheral hypoperfusion.

Clinical Trial Description


Study Design

Related Conditions & MeSH terms

NCT number NCT05209230
Study type Interventional
Source Hospices Civils de Lyon
Contact RUSTE Martin, MD, Msc
Phone +33472118956
Status Recruiting
Phase N/A
Start date April 15, 2022
Completion date June 16, 2025

See also
  Status Clinical Trial Phase
Withdrawn NCT04830982 - Safety and Efficacy of IV Diazoxide as an Additive to Hyperkalemic Cardioplegia in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass Phase 1
Completed NCT00213746 - Evaluation of Myocardial Viability by Means of Low-dose Dobutamine Gated SPECT (the DOGS Study) N/A
Active, not recruiting NCT00123695 - Serial Echocardiography After Subarachnoid Hemorrhage N/A
Terminated NCT01500785 - Intracoronary Administration of Levosimendan in Cardiac Surgery Patients Phase 4
Completed NCT06450912 - Wall Strain Index Ratio as a Biomarker for Mechanical Complication of Hemorrhagic Myocardial Infarction
Completed NCT02545426 - Myocardial Stunning During Hemodialysis: Role of Dialyste Calcium Concentration N/A
Completed NCT01179802 - Exercise-induced Changes in Cardiac Function & Morphology N/A
Not yet recruiting NCT06308107 - Safety and Feasibility of Hyperkalemic Cardioplegia With Diazoxide in Cardiac Surgery (CPG-DZX) Trial Phase 1
Recruiting NCT04448639 - Stunning in Takotsubo Versus Acute Myocardial Infarction
Withdrawn NCT02770183 - Rate of Left Ventricular Systolic Function's Recuperation After Cardiac Surgery With Extracorporeal Circulation.
Recruiting NCT05669144 - Co-transplantation of Mesenchymal Stem Cell Derived Exosomes and Autologous Mitochondria for Patients Candidate for CABG Surgery Phase 1/Phase 2
Withdrawn NCT02687269 - Ranolazine a Potential New Therapeutic Application Phase 4