Clinical Trials Logo

Myocardial Infraction clinical trials

View clinical trials related to Myocardial Infraction.

Filter by:
  • Completed  
  • Page 1

NCT ID: NCT01991093 Completed - Clinical trials for Coronary Artery Disease (CAD)

Multiple Electrode Aggregometry & Clopidogrel Resistance

Start date: June 2014
Phase:
Study type: Observational

Antiplatelet therapy with aspirin-clopidogrel reduces the risk of cardiovascular episodes after percutaneous coronary intervention (PCI) in patients with acute coronary syndromes. However, a significant number of patients experience recurrent events while on such therapy. The individual response to dual antiplatelet therapy is not uniform, and consistent findings across multiple investigations support the association between a lower degree of platelet inhibition, high on-treatment platelet reactivity, and the occurrence of atherothrombotic events [1, 2]. Particularly in diabetic patients, clopidogrel resistance is more prevalent compared with non-diabetics [3,4], which seems to contribute to the increased atherothrombotic risk in these patients compared with those without diabetes mellitus (DM) [5]. A number of platelet function instruments have now become available that are simple to use and can be utilized as point-of-care (POC) instruments in order to monitor antiplatelet therapy and potentially assess the risk of a recurrent event [6].