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NCT00032695 Clinical Trial

Treatment of AIDS Vacuolar Myelopathy With Methionine

Myelopathy Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00032695
Other study ID # R01NS035745
Secondary ID
Status Completed
Phase Phase 3
First received March 28, 2002
Last updated May 12, 2006

Study information
Verified date November 2005
Source National Institute of Neurological Disorders and Stroke (NINDS)
Contact n/a
Is FDA regulated No
Health authority United States: Federal Government
Study type Interventional

Clinical Trial Summary

The purpose of this study is to determine whether methionine, an amino acid present in low doses in the normal diet, can improve myelopathy or stop its progression.

Description:

Myelopathy is usually a late complication of AIDS, and until recently its symptoms were rarely recognized, masked by the general state of disability or the presence of other neurological complications. With prolonged survival and improved quality of life of HIV-infected patients, myelopathy is increasingly becoming a common source of disability. The cause of AIDS-myelopathy is unknown, but it is probably an indirect effect of the long-term presence of the HIV virus in the nervous system rather than the result of a direct infection. The purpose of this study is to determine whether methionine, an amino acid present in low doses in the normal diet, can improve myelopathy or stop its progression.

Recruitment information / eligibility
Status Completed
Enrollment 56
Est. completion date
Est. primary completion date
Accepts healthy volunteers No
Gender Both
Age group 18 Years to 80 Years
Eligibility Between 18 and 80 years of age

Study Design

Allocation: Randomized, Masking: Double-Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Drug:
• methionine

Locations
Country Name City State
United States Beth Israel Medical Center New York New York

Sponsors (1)
Lead Sponsor Collaborator
National Institute of Neurological Disorders and Stroke (NINDS)

Country where clinical trial is conducted

United States, 

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