Clinical Trials Logo

Clinical Trial Summary

The purpose of this trial is to assess fusion rates in 3 and 4 level ACDFs in patients implanted with DePuy Conduit 3D printed titanium cages supplemented with SKYLINE Anterior Cervical Plate System and 1 CC DBM. This will be a non-inferiority study, looking to show that Synthes Conduit 3D printed titanium cages fuse as well as cages.


Clinical Trial Description

This is a prospective, single arm study of clinical and radiological outcomes from anterior cervical discectomy and fusions for cervical spondylosis. 58 Patients undergoing 3 to 4 level ACDF procedures from C2-T1 will be enrolled. Patients will be implanted with DePuy Conduit Titanium ACDF cage (DePuy Synthes, Raynham, MA). A retrospective comparision group will be used. The retrospective group will include 58 consecutive patients undergoing 3-4 level ACDFs with milled allograft. This single-centered study will enroll up to 58 subjects, with subjects followed for 24 months post-surgery. All subjects enrolled in the study will be recruited from a pool of subjects eligible for three or four level anterior cervical fusion surgeries. The inclusion/exclusion criteria are listed below. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05696470
Study type Observational [Patient Registry]
Source Ohio State University
Contact
Status Active, not recruiting
Phase
Start date March 31, 2021
Completion date December 31, 2025

See also
  Status Clinical Trial Phase
Completed NCT03733886 - Burst Spinal Cord Stimulation for Neuropathic Pain. N/A
Completed NCT03835182 - Efficacy of Ultrasound Versus Short Wave Diathermy in the Treatment of a Slipped Disc of the Lower Back N/A
Completed NCT04169477 - Comparison of Two Modes of Transcutaneous Electrical Nerve Stimulation (TENS) in Chronic Neuropathic Radiculalgia N/A
Completed NCT02265848 - High Frequency Stimulation Trials in Patients With Precision Spinal Cord Stimulator System Phase 4
Not yet recruiting NCT05487690 - Application of 3D Printing Guide Plate in Spinal Minimally Invasive and Interventional Surgeries N/A
Recruiting NCT04909138 - Intermittent Dosing of Dorsal Root Ganglion Stimulation as an Alternate Paradigm to Continuous Low-Frequency Therapy N/A
Completed NCT05533723 - Comparison Between Endoscopic Epidural Neuroplasty and Percutaneous Epidural Neuroplasty in Low Back and Radicular Pain
Not yet recruiting NCT06041347 - Learning Curve for the Visualization of Sacral Plexus on TVS
Completed NCT02939482 - A Study Comparison of Clinical Outcome After Different Rate of Infusion in Caudal Epidural Steroid Injection N/A
Recruiting NCT05732818 - Lumbar Operatively Inserted PerQdisc Artificial Implant Following Nuclectomy 3 N/A
Active, not recruiting NCT04559295 - Bone Marrow Concentrate (BMC) Injection in Intervertebral Discs Phase 2/Phase 3
Completed NCT02644421 - Clinical Trial to Evaluate the Safety and Analgesic Efficacy of VVZ-149 in Lumbar Radiculopathy (Sciatica) Phase 1
Recruiting NCT06193265 - Management of Lumbar Discectomy by Endoscopy and Conventional Microscopic Discectomy
Recruiting NCT05145842 - The Effect of Combination of Ultrasound and Flouroscopy Guidance in Caudal Epidural Injections N/A
Withdrawn NCT03327272 - Impact of Local Steroid Application in Extreme Lateral Lumbar Interbody Fusion Phase 3
Withdrawn NCT02196883 - Steroid Injections Given at the "Level of MRI Pathology" Versus at the "Level of Clinical Symptoms" to See if One is More Effective Than the Other. N/A
Terminated NCT01850771 - Regenexx™ PL-Disc Versus Steroid Epidurals for Lumbar Radiculopathy N/A
Completed NCT02130258 - Somatosensory Profiling in Radicular Pain Patients And it's Correlation With Treatment Outcome N/A
Withdrawn NCT05347108 - Real-Time Accurate Pathology Inspection and Decompression Study
Recruiting NCT05952167 - Evaluation of the Impact of Tractions vs. Placebo Tractions in Patients With Cervical Radiculopathy N/A