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Clinical Trial Summary

Study of the combination of luspatercept in low-risk myelodysplastic syndrom (LR-MDS) without ring sideroblasts (RS) having failed or being ineligible to ESA

Clinical Trial Description

Part A of the trial=Dose-finding Study: Determination the optimal dose level in terms of both toxicity and efficacy for luspatercept + ESA Part B : Determination of the superiority and efficacy of the association Luspatercept+ESA (erythroipoiesis Stimulating Agent) over luspatercept alone in patients with lower risk MDS who failed to achieve a response or who subsequently relapsed after ESA, wihtout disease progression ;

Study Design

Related Conditions & MeSH terms

NCT number NCT05181735
Study type Interventional
Source Groupe Francophone des Myelodysplasies
Contact Fatiha CHERMAT
Phone +33 1 71 20 70 59
Email [email protected]
Status Not yet recruiting
Phase Phase 1/Phase 2
Start date February 1, 2022
Completion date August 1, 2027

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