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Clinical Trial Summary

The main purpose of this study is to verify the safety and potential effectiveness of CART cells combined with peptide specific dendritic cell in relapsed/refractory leukemia.


Clinical Trial Description

A prospective study to evaluate the safety and efficacy of Chimeric antigen receptor T cells combined with Eps8 or WT1(Wilms tumor 1) peptide specific dendritic cell for patients with relapsed/refractory leukemia. There are options for CAR-targets: CD19, CD20, CD22 and CD10 for acute lymphoblastic leukemia; CD33, CD38 CD56, CD117, CD123, CD34 and Muc1 for acute myeloid leukemia and Myelodysplastic Syndrome. Progression free survival, overall Survival, overall response rate, and duration of response were monitored. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03291444
Study type Interventional
Source Zhujiang Hospital
Contact Sanfang Tu, M.D, Ph.D
Phone 86-20-62782322
Email doctortutu@163.com
Status Recruiting
Phase Phase 1
Start date May 5, 2018
Completion date June 1, 2025

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