A Phase 1 Study of AMG 330 in Subjects With Myeloid Malignancies

Status Terminated

Clinical Trial Summary

The purpose of this First-in-Human Phase 1 study is to determine if AMG 330 given as a continuous IV infusion is safe and tolerable in adult subjects that have myeloid malignancies, and to determine the maximum tolerated dose and/or a biologically active dose. The study will be conducted in multiple sites and test increasing doses of AMG 330. The safety of subjects will be monitored by intensive assessment of vital signs, electrocardiograms, physical examinations, and laboratory tests.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02520427
Study type	Interventional
Source	Amgen
Contact
Status	Terminated
Phase	Phase 1
Start date	October 20, 2015
Completion date	January 9, 2022

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