Randomized Controlled Trial of Doxycycline to Prevent Acquisition of Mycoplasma Pneumoniae in an Outbreak Setting

Mycoplasma Pneumoniae Clinical Trial

Official title:

A Double-Blind, Randomized Placebo-Controlled Trial of Doxycycline for Chemoprophylaxis in the Setting of an Outbreak of Mycoplasma Pneumoniae

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00207584
• Other study ID #: CDC-NCHSTP-9997
• Status: Completed
• Phase: N/A
• First received: September 13, 2005
• Last updated: September 13, 2005
• Start date: January 1994
• Est. completion date: April 1994

Study information

• Verified date: September 2005
• Source: Centers for Disease Control and Prevention
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Federal Government
• Study type: Interventional

Clinical Trial Summary

This study was designed to determine whether taking daily doxycycline during an outbreak of Mycoplasma pneumoniae could prevent a person from getting infected and interrupt ongoing disease transmission during an outbreak. Doxycycline is a treatment for Mycoplasma pneumoniae, but it is not certain that the drug could prevent disease if used prophylactically.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 0
• Est. completion date: April 1994
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Working at hospital facility where outbreak of Mycoplasma pneumoniae occured

Exclusion Criteria:

• Pregnant, on antiseizure medications, allergic to macrolide antibiotics

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double-Blind

Related Conditions & MeSH terms

• Mycoplasma Infections
• Mycoplasma Pneumoniae
• Pleuropneumonia
• Pneumonia
• Pneumonia, Mycoplasma

Intervention

Drug:
• Doxycycline treatment

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Centers for Disease Control and Prevention