Effects of Oral Steroid in Mycoplasma Pneumoniae Pneumonia

Mycoplasma Pneumoniae Pneumonia Clinical Trial

Official title: Effects of Oral Steroid in Mycoplasma Pneumoniae Pneumonia With Lobar Consolidation or Pleural Effusion in Children

Status Recruiting

Clinical Trial Summary

Mycoplasma pneumoniae is one of the most common causes of community-acquired pneumonia in children. The clinical course is typically self-limited and benign; however, rare cases of severe pneumonia can develop despite appropriate antibiotic therapy. The investigators aim to study the effects of prednisolone on severe M. pneumoniae pneumonia with lobar consolidation or pleural effusion in children.

Clinical Trial Description

Mycoplasma pneumoniae is one of the most common causes of community-acquired pneumonia in children. The clinical course is typically self-limited and benign; however, rare cases of severe pneumonia can develop despite appropriate antibiotic therapy. The investigators aim to study the effects of prednisolone on severe M. pneumoniae pneumonia with lobar consolidation or pleural effusion in children. Participants will be randomly assigned (1:1 ratio) to receive either prednisone 1 mg/kg/d daily for 5 days or none. The primary endpoint was fever duration and analysed by intention to treat. ;

Related Conditions & MeSH terms

• Mycoplasma Infections
• Mycoplasma Pneumoniae Pneumonia
• Pleuropneumonia
• Pneumonia
• Pneumonia, Mycoplasma

• NCT number: NCT02618057
• Study type: Interventional
• Source: Seoul National University Hospital
• Contact: Ki Wook Yun, M.D., Ph.D.
• Phone: 82-2-2072-4909
• Email: pedwilly@gmail.com
• Status: Recruiting
• Phase: Phase 4
• Start date: June 2016
• Completion date: December 2020