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MMF Versus CYC in the Induction Therapy of Pediatric Active Proliferative LN — MyCITS  

Lupus Nephritis Clinical Trial

Official title:
Mycophenolate Mofetil Versus Cyclophosphamide in the Induction Therapy of Pediatric Patients With Active Proliferative Lupus Nephritis: A Prospective, Randomized, Multicenter, Open-label, Parallel-arm Study

Clinical Trial Summary

A prospective, randomized, multicenter, open-label, parallel-arm Study to compare effectiveness of mycophenolate mofetil versus cyclophosphamide in the Induction Therapy of pediatric patients with Active Proliferative Lupus Nephritis in Chinese population

Clinical Trial Description

Scattered research in adults showed that both mycophenolate mofetil (MMF) and cyclophosphamide (CYC) can be used in the induction therapy of lupus nephritis. however data is limited in children.Therefore, the purpose of this study is to observe and compare the efficacy and safety of MMF and CYC as induction therapy for children with proliferative lupus nephritis through a multi-center open randomized controlled study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05495893
Study type Interventional
Source Second Xiangya Hospital of Central South University
Contact Xiaochuan Wu
Phone 0731-85295259
Email 503151@csu.edu.cn
Status Recruiting
Phase Phase 4
Start date July 25, 2022
Completion date May 31, 2025
View Details
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