Rheumatoid Arthritis Clinical Trial
Official title:
Therapy of Antibody-mediated Autoimmune Diseases by Bortezomib (TAVAB)
The aim of this pilot study is to investigate the application of proteasome inhibitor Bortezomib (Velcade®, approved for therapy of multiple myeloma) in patients with therapy-refractory antibody-mediated autoimmune diseases. The investigators hypothesis is that the proteasome inhibition will lead to reduced antibody titers and improved clinical outcome.
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