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Myalgia clinical trials

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NCT ID: NCT06444763 Not yet recruiting - Joint Pain Clinical Trials

Effect of Maolactin™ FMR on Exercise Recovery, Inflammation and Muscle Comfort in an Otherwise Healthy Population

Start date: July 31, 2024
Phase: Phase 3
Study type: Interventional

This is a double blind, randomised, placebo-controlled, parallel-group trial to evaluate the effect of Maolactin FMR supplementation on chronic inflammation, mobility and muscle and joint pain in an otherwise healthy population of adults 45-65 years old over 14 weeks with 12 weeks supplementation. This is PART B of the study.

NCT ID: NCT06436781 Not yet recruiting - Muscle Fatigue Clinical Trials

Effect of Maolactin™ FMR on Exercise Recovery, Inflammation, and Muscle Comfort in an Otherwise Healthy Population

Start date: July 31, 2024
Phase: Phase 3
Study type: Interventional

This is a double blind, randomised, placebo-controlled, parallel-group trial to evaluate the effect of Maolactin FMR supplementation on post exercise inflammation, exercise recovery and muscle fatigue and pain in an otherwise healthy population of adults 18-65 years old over 10 weeks with 8 weeks of supplementation. This is PART A of the study.

NCT ID: NCT06225388 Not yet recruiting - Heart Rate Clinical Trials

Effect of Wearing a Compression Sock During Running on Muscle Soreness in Distance Runners.

Start date: January 20, 2024
Phase: N/A
Study type: Interventional

Running is the most popular physical activity worldwide. Although running provides many health benefits, it is often associated with injuries and symptoms such as delayed onset muscle soreness. There is still a paucity of interventions that can effectively minimise these symptoms in distance runners.

NCT ID: NCT05961501 Not yet recruiting - Headache Clinical Trials

The Effectiveness of CBD and CBN in the Treatment of Facial Pain and Headache of Muscular Origin

Start date: July 2024
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of the study is to evaluate the effectiveness of an aqueous solution containing CBD and CBN in the management of Facial Pain and Headache of Muscular Origin. A randomized (block randomization), double-blind, two-arm controlled trial will involve 42 adult patients diagnosed with Facial Pain and Headache of Muscular Origin which is lasting more than 3 months on the basis of clinical examination. Qualified study participants will be randomly assigned to two groups. The studied group will receive tan aqueous solution containing CBD and CBN, to drink at home in the dose determined by the attending physician, while the control group will receive an aqueous solution of placebo, to drink at home in the dose determined by the attending physician during this time. Each subject will be tested on the qualification day (D0), on 20 days after D0 (D20), and then 40 (D40) and 60 (D60) days after the qualification day using electromyography (EMG), pressure pain threshold test (PPT), clinical examination and surveys.

NCT ID: NCT04872374 Not yet recruiting - Clinical trials for Inflammatory Response

Effects of Parmigiano Reggiano on Skeletal Muscle Damage in Older Adults

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

Aging is associated with the loss of muscle mass and function (sarcopenia) and reduced tissue regenerative capacity. Eccentric exercise (ECC) is a model of RET that can be used with the elderly, due to the ability of the muscle to combine high muscle strength production with low energy cost. ECC contractions are significantly more damaging to the muscles and produce greater muscle strength, for these reasons there is a greater risk of inducing muscle damage before the muscle is able to adapt. Parmigiano Reggiano (PR) has some peculiar bromatological characteristics. The proteins contained in it, and in particular the potentially bioactive peptide sequences, can rapidly provide the amino acids necessary to promote muscle growth and repair during exercise. Furthermore, PR can be an important source of fatty acids, of which a significant amount of short-chain fatty acids (SCFA) which are known to have important clinical effects on body composition and metabolic health and can have a systemic anti-inflammatory effect. Therefore, the central hypothes is that PR consumed during RET can provide more energy substrates and improve muscle recovery. To date, no studies have studied its function on recovery from exercise nor in the elderly.

NCT ID: NCT04426123 Not yet recruiting - Myofascial Pain Clinical Trials

Masseter Myofascial Pain Relief Following an Intra-muscular Injection With Botulinum Toxin Type A.

Start date: July 1, 2020
Phase: Phase 2
Study type: Interventional

Investigating the effect of a single intramuscular injection with botulinum toxin (BTX) compared to NaCl in patients with jaw muscle myalgia. This investigation is designed as an double blind multicenter pilot study for hypothesis generation on 48 patients with chronic jaw muscle myalgia at four specialist dental clinics. The subjects visit the clinic on 3 predefined occasions, one telephone call and one scheduled evaluation by mail. The objective is primarily to evaluate the change in number of days with pain at two months following one session of BTX injections of the masseter and temporalis muscles in subjects with jaw muscle myalgia pain. The outcome of this study will serve as a basis for a later randomized controlled trial

NCT ID: NCT03632928 Not yet recruiting - Migraine Disorders Clinical Trials

Day to Day Variation of Pressure Pain Threshold and Muscle Hardness

Start date: September 2018
Phase:
Study type: Observational

The aim is to establish how headache and migraine can affect muscle hardness and tenderness in migraine patients

NCT ID: NCT03566394 Not yet recruiting - Clinical trials for Invasive Breast Cancer

Prophylactic Gabapentin for Taxane-Induced Arthralgia and Myalgia Syndrome in Breast Cancer Patients Undergoing Adjuvant Chemotherapy

Start date: July 2, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

Taxane-induced arthralgia and myalgia syndrome (TAMS) is one of the most common side effects of taxane chemotherapy. This prospective randomized controlled trial will evaluate the efficacy of gabapentin administered prophylactically on days -2 to +5 during the taxane-portion of chemotherapy for adjuvant breast cancer patients on reducing TAMS. This will be compared to observation alone.

NCT ID: NCT03427216 Not yet recruiting - Clinical trials for Pelvic Floor Dyssynergia

Baclofen/Diazepam Supps for Treatment of Pelvic Floor Myalgia

BDS
Start date: September 1, 2018
Phase: N/A
Study type: Interventional

This study is a randomized, placebo controlled double blind cross over trial. Patients presenting with pelvic floor myalgia will be asked to complete a series of standardized questionnaires to assess their pain, quality of life and sexual function and satisfaction. They will be randomized to either a treatment group or placebo group and will use the supplied suppositories once daily for 2 months. They will then undergo a one month "washout" after which they will be placed in the cross over group for a second two months of treatment. Primary outcome measure: change in Visual Analogue Scale for Pain (VAS-P) scores before and after treatment Secondary outcome measures: change in Female Sexual Function Index (FSFI), Patient Global Impression of Improvement (PGI-I), and Short Form Health Survey (SF-12) before and after treatment

NCT ID: NCT03421028 Not yet recruiting - Sleep Clinical Trials

Evaluation of Biofeedback Therapy Efficiency in Masticatory Muscles Pain Management

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

This study evaluates beneficial effects of biofeedback therapy in reducing pain and increased tension of muscles occurring in patients with temporomandibular disorders (TMD). During the study Electromyography Biofeedback (EMG-Biofeedback)- assisted training lowering muscle tension will be used. The patients will undergo 4 or 8 meetings of EMG-Biofeedback - assisted training Than the patients will be reevaluated after 6 and 12 weeks.