MutYH-associated Polyposis Clinical Trial
Official title:
Diagnosis and Treatment of Russian Patients With MutYH-associated Polyposis
This is single-center, prospective, non-randomized study
The study will include patients with more than 3 polyps, without mutations in the APC gene. Using molecular genetic research methods (polymerase chain reaction, SSCP, sequencing by Sanger method) mutations in the MutYH gene will be studied. For all patients with mutations in the MutYH gene, an optimal diagnostic algorithm will be developed. The significance of monoallelic mutations in the MutYH gene will be determined. Clinical monitoring will be defined. Optimal amount of surgical intervention will be suggested. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT06163365 -
Inherited Cancer Early Diagnosis (ICED) Study
|