Musculoskeletal Imaging of Runners

Musculoskeletal Injury Clinical Trial

Official title:

Musculoskeletal Imaging of Runners

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT04385472
• Other study ID #: 13823/001
• Status: Active, not recruiting
• Start date: April 1, 2019
• Est. completion date: December 1, 2021

Study information

• Verified date: May 2020
• Source: Royal National Orthopaedic Hospital NHS Trust
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The investigators aimed to assess the impact of long-distance running on musculoskeletal system of runners, by doing high resolution magnetic resonance imaging analysis before and after marathon running.

Description:

Rationale for the study: This research will examine a key modifiable risk factor for health and well- being: exercise. Regular exercise is highly recommended by healthcare professionals because the whole body benefits, including cardiorespiratory, musculoskeletal systems and mental wellbeing. Long-distance running is a popular physical activity with more than 30 million individuals running marathons each year. The increasing participation of first-time runners, including older people, has been linked to a rise in related injuries. The ideal dose of exercise is not known and overdosage affects some musculoskeletal tissues and joints more than others. Overdoing a specific amount of exercise and the presence of chronic injuries may pose a great risk on the joints, leading to serious conditions such as osteoarthritis, musculoskeletal injuries, tendinopathy. However, it is not yet clear whether a high dose of exercise such as marathon running damages the musculoskeletal system and there is a growing need for research in the area of running science to better understand this.

Aim: This research aims to do musculoskeletal imaging before and after long-distance running using 3 Tesla magnetic resonance imaging and to provide evidence on how much exercise people should undertake and how to minimise injury.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 52
• Est. completion date: December 1, 2021
• Est. primary completion date: February 1, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

• no previous marathon participations

• no present or previous history of hip injuries or surgeries

• asymptomatic hip joints

• no contradindications to hip MRI scanning

Exclusion Criteria:

• pregnant or breastfeeding women

• individuals aged <18 years

• claustrophobia

• history of anxiety or panic attacks

• known hip problems

Related Conditions & MeSH terms

• Musculoskeletal Injury

Intervention

Radiation:
• 3T MRI
The main method used will be 3 Tesla MRI, which is a high resolution imaging technique. The participants will be asked to undergo musculoskeletal MRI scanning (pelvis and lumbar spine).MRI is a non-invasive procedure which excludes the risk of radiation (in comparison to other imaging modalities: X-ray, CT

Locations

Country	Name	City	State
United Kingdom	Royal National Orthopaedic Hospital	London

Sponsors (1)

Lead Sponsor	Collaborator
Royal National Orthopaedic Hospital NHS Trust

Country where clinical trial is conducted

United Kingdom, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in radiographic score after marathon running		up to 1 year
Primary	Change in self-reported hip questionnaire after marathon running		up to 1 year
Secondary	Number of participants who finished the training for/and the marathon vs not finishing		up to 4 months