Effect of Beetroot Juice Supplements on Lower-limb Strength in Females

Muscular Endurance Clinical Trial

Official title:

Acute Effects of Beetroot Juice Supplements on Lower-limb Strength and Muscular Endurance in Physically Active Women: Double-blind Crossover Randomized Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04987619
• Other study ID #: BEETROOT JUICE
• Status: Completed
• Phase: N/A
• Start date: July 5, 2021
• Est. completion date: August 29, 2021

Study information

• Verified date: July 2021
• Source: Maimónides Biomedical Research Institute of Córdoba
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study aims to evaluate the effects of beetroot juice supplements on lower-limb strength and muscular endurance in physically active women, due to the presence of NO3- in beetroot juice.

Description:

Beetroot juice (BJR) is used as an ergogenic aid, but no study has analyzed its' effects on explosive force production in physically active women. It has been proposed that females could blunt reduction of NO2- to NO based on a higher oxidative skeletal muscle phenotype than males. However, it has been observed a higher increase on plasma NO2- levels after supplementation compared to and a greater enhancement on muscle contractile function. Based on the absence of any study that has analyzed the effect of NO3- supplements on jump ability and power production on weightlifting on female population; the purpose of this study will be to investigate the possible ergogenic effect of BJR on physically active women on explosive force production and muscular endurance in a lower-limb body weightlifting protocol, due to the presence of NO3- in BJR and its effects.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 11
• Est. completion date: August 29, 2021
• Est. primary completion date: August 29, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years to 30 Years

Eligibility

Inclusion Criteria:

• Physically active females with 18-30 years of age
• More than 6 months on RT training programs
• Be familiarized with back squat, leg press and leg extension exercises
• Not consuming any type of nutritional supplement or anabolic substances in the previous three months or during the study
• Not suffering from a musculoskeletal injury that could interfere with the exercise protocol during the investigation

Exclusion Criteria:

• None

Related Conditions & MeSH terms

• Muscular Endurance

Intervention

Dietary Supplement:
• Beetroot juice
Subjects will drink juice 120 minutes before each visit

Other:
• Capri-Sun
70 mL of blackcurrant beverage, which is depleted of NO3- will be taken 120 min before each visit.

Locations

Country	Name	City	State
Brazil	Studies Research Group in Neuromuscular Responses (GEPREN), University of Lavras	Lavras
Spain	Department of Food Science and Technology, Rabanales University Campus, University of Cordoba	Córdoba
Spain	Department of Nursing Pharmacology and Physiotherapy, Faculty of Medicine and Nursing, University of Córdoba	Córdoba
Spain	Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba	Córdoba
Spain	Metabolism and Investigation Unit, Maimonides Biomedical Research Institute of Cordoba (IMIBIC),Reina Sofia University Hospital, University of Cordoba	Córdoba
Spain	Departamento de Motricidad Humana y Rendimiento Deportivo, Universidad de Sevilla	Sevilla

Sponsors (1)

Lead Sponsor	Collaborator
Maimónides Biomedical Research Institute of Córdoba

Countries where clinical trial is conducted

Brazil,  Spain, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change of height reached in jump	Evaluated through CMJ (Counter movement jump) test with a recovery period of 45 seconds between jumps.	Week 1, 2 and 3.
Secondary	Movement velocity	Evaluated at 50% and 75% repetition maximum (RM)	Visit 1 (week 1), 2 (week 2) and 3 (week 3).
Secondary	Power on back squat	Evaluated at 50% and 75% repetition maximum (RM)	Visit 1 (week 1), 2 (week 2) and 3 (week 3).
Secondary	Muscular endurance test	The test consists of three exercises: back squat, leg press and leg extension. Three series will be performed until concentric failure at 75% RM, three minutes of rest between each series.	Visit 1 (week 1), 2 (week 2) and 3 (week 3).
Secondary	Rating of perceived exertion (RPE).	Immediately at the end of the muscular endurance test, participants will be instructed to report their RPE using a scale 1-10 (worse to better outcome).	Visit 1 (week 1), 2 (week 2) and 3 (week 3).