Changes in the Force-velocity Relationship of Knee Muscles After ACL Reconstruction

Muscle Weakness Clinical Trial

— FoVeA  

Official title:

Changes in the Force-velocity Relationship of Knee Muscles After ACL Reconstruction

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05712109
• Other study ID #: FoVeA
• Status: Completed
• Start date: January 15, 2017
• Est. completion date: February 5, 2023

Study information

• Verified date: March 2023
• Source: University Hospital, Caen
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

Anterior cruciate ligament (ACL) tear is a frequent and devastating injury in sport, especially in pivoting-contact disciplines. In many cases, athletes will undergo an ACL reconstruction (ACL-R) for recovering knee stability, preventing further injuries and returning to sport (RTS). Among the criteria for RTS, knee muscle strength is the most used objective criteria and especially the symmetry of knee flexors and/or extensors between the operated and uninjured knee. Isokinetic testing of knee muscle strength is considered as a reference for knee muscle testing during the follow up stages after ACL-R. This evaluation allows to measure the strength (torque) of knee flexors and extensors at several angular velocities. However, there is no relevant litterature about the force-velocity (Fo-v) relationship of knee flexors and extensors after ACL-R. The present study aimed to evaluate and test the differences between the Fo-v relationship parameters between the operated and uninjured knees at 4 months and 8 months after ACL-R, using the 2-points method with isokinetic testing. Also, the investigators aimed to test the impact of the type of surgery (patellar tendon autograft vs. hamstring tendon autograft) on the Fo-v relationship after ACL-R

Recruitment information / eligibility

• Status: Completed
• Enrollment: 103
• Est. completion date: February 5, 2023
• Est. primary completion date: January 15, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 16 Years to 55 Years

Eligibility

Inclusion Criteria:

• Patients who have had an ACL reconstruction surgery (isolated or associated with other meniscal or ligamentary surgery)
• Patient included in the sport medicine follow-up protocole with intermediate and final isokinetic muscular assessment at 4 months and8 months after surgery respectively
• Patients who completed both tests at the 60°/s and 240°/s velocities

Exclusion Criteria:

• Patient who did not participate in all follow-up consultations and isokinetic muscular assessments
• Cognitive or sensory impairment making it impossible to understand the information form
• Neurological, traumatic or osteoarticular history responsible for muscle imbalance prior to surgery

Related Conditions & MeSH terms

• Anterior Cruciate Ligament Injuries
• Muscle Weakness

Intervention

Other:
• Follow-up after Anterior cruciate ligament reconstruction
The patients were referred to the sport medicine department for the post ACL-R follow-up including isokinetic knee muscle strength evaluations at 4 months and 8.months after the surgery

Locations

Country	Name	City	State
France	CHU Caen Normandie	Caen

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Caen

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in strength	Measurement of knee extensors and flexors peak strength (in newton.meter, Nm) on isokinetic dynamometer at two angular velocities of 60°/s and 240°/s respectively	Time Frame: ACL group: Two evaluations on both injured and healthy knees: (1) 4 months after surgery and (2) 8 months after surgery; Routine practice following guidelines
Primary	Change in the force-velocity relationship	Calculation of the corresponding slope and maximal force (Y-intercept) of the regression line of the force-velocity curve	Time Frame: ACL group: Two evaluations on both injured and healthy knees: (1) 4 months after surgery and (2) 8 months after surgery; Routine practice following guidelines
Secondary	Individual characteristics	Personal characteristics recorded in the medical report as age, gender, type of sport and sport level of practice and return to sport after the surgery	Time Frame: ACL group: Two evaluations on both injured and healthy knees: (1) 4 months after surgery and (2) 8 months after surgery; Routine practice following guidelines
Secondary	Injury characteristics	Injury characteristics recorded in the medical report as the type of injury (ACL only, ACL and meniscus, ACL with other ligament injury, recurrent ACL injury) the time before surgery, the type of rehabilitation before and after surgery	Time Frame: ACL group: Two evaluations on both injured and healthy knees: (1) 4 months after surgery and (2) 8 months after surgery; Routine practice following guidelines
Secondary	Surgery characteristics	Surgery characteristics recorded in the medical report as the type of surgery, the surgery duration and tourniquet time	Time Frame: ACL group: Two evaluations on both injured and healthy knees: (1) 4 months after surgery and (2) 8 months after surgery; Routine practice following guidelines