Physiologic Effects of PRMS & Testosterone in the Debilitated Elderly

Muscle Weakness Clinical Trial

Official title:

Physiologic Effects of PRMS & Testosterone in the Debilitated Elderly

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00018356
• Other study ID #: AGCG-007-98S
• Status: Completed
• Phase: Phase 4
• First received: July 3, 2001
• Last updated: June 22, 2011
• Start date: January 1999
• Est. completion date: August 2006

Study information

• Verified date: June 2011
• Source: VA Office of Research and Development
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Federal Government
• Study type: Interventional

Clinical Trial Summary

This study's primary objective is to determine the independent and combined effects of progressive resistance muscle strength training and testosterone on the development of sustainable improvements in physical function.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 88
• Est. completion date: August 2006
• Est. primary completion date: July 2006
• Accepts healthy volunteers: No
• Gender: Male
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

The study will be limited to those patients who are metabolically stable and free of metastatic cancer and limiting end organ disease. Their total serum testosterone must be less than 480 and PSA less than 10.

Exclusion Criteria:

Study Design

N/A

Related Conditions & MeSH terms

• Muscle Weakness
• Muscular Atrophy
• Paresis

Intervention

Procedure:
• exercise

Drug:
• testosterone

Locations

Country	Name	City	State
United States	Central Arkansas VHS Eugene J. Towbin Healthcare Ctr, Little Rock	No. Little Rock	Arkansas

Sponsors (1)

Lead Sponsor	Collaborator
VA Office of Research and Development

Country where clinical trial is conducted

United States, 

References & Publications (1)

Sullivan DH, Roberson PK, Johnson LE, Bishara O, Evans WJ, Smith ES, Price JA. Effects of muscle strength training and testosterone in frail elderly males. Med Sci Sports Exerc. 2005 Oct;37(10):1664-72. — View Citation