Muscle Trauma Clinical Trial
Although deep anesthesia can produce skeleton muscle relaxation,unnecessary deep anesthesia
often had adverse cardiac effects and was related to 2-year mortality in cancer patients.The
use of muscle relaxants allowed the depth of anesthesia to be optimized.However, for many
anesthesiologists,in fear of residual postoperative neuromuscular blockade,intraoprative
administration of muscle relaxants had to be minimized in spite of poor surgical conditions.
This study, however, is designed to test the hypothesis that profound neuromusclular
blockade reduces muscle trauma caused by self-retaining retractor and thus cut down
postoperative analgesic requirement.On the other hand,profound muscle relaxation can
decrease postoperative diaphragmatic dysfunction and abdominal muscle trauma, which can
improve postoperative pulmonary function.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT01228162 -
Influence of Muscle Relaxation With Rocuronium Bromide During General Anaesthesia on Muscle Trauma and Postoperative Analgetic Consumption in Patients With Total Hip Prosthesis Implantation
|
Phase 4 |