Effects of Parmigiano Reggiano on Skeletal Muscle Damage in Older Adults

Status Not yet recruiting

Clinical Trial Summary

Aging is associated with the loss of muscle mass and function (sarcopenia) and reduced tissue regenerative capacity. Eccentric exercise (ECC) is a model of RET that can be used with the elderly, due to the ability of the muscle to combine high muscle strength production with low energy cost. ECC contractions are significantly more damaging to the muscles and produce greater muscle strength, for these reasons there is a greater risk of inducing muscle damage before the muscle is able to adapt. Parmigiano Reggiano (PR) has some peculiar bromatological characteristics. The proteins contained in it, and in particular the potentially bioactive peptide sequences, can rapidly provide the amino acids necessary to promote muscle growth and repair during exercise. Furthermore, PR can be an important source of fatty acids, of which a significant amount of short-chain fatty acids (SCFA) which are known to have important clinical effects on body composition and metabolic health and can have a systemic anti-inflammatory effect. Therefore, the central hypothes is that PR consumed during RET can provide more energy substrates and improve muscle recovery. To date, no studies have studied its function on recovery from exercise nor in the elderly.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04872374
Study type	Interventional
Source	University of Padova
Contact	Tatiana Moro, PhD
Phone	0498275306
Email	tatiana.moro@unipd.it
Status	Not yet recruiting
Phase	N/A
Start date	May 1, 2021
Completion date	March 1, 2022

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04496154` - Omega-3 to Reduce Diabetes Risk in Subjects With High Number of Particles That Carry "Bad Cholesterol" in the Blood	N/A
Enrolling by invitation	`NCT05020210` - Effect of Early Treatment With Sivelestat Sodium in ARDS Patients
Completed	`NCT04084301` - Impact of Cardiopulmonary Bypass Flow on Renal Oxygenation, Blood Flow and Tubular Injury	N/A
Completed	`NCT04597983` - Effect of 8-week Intake of 2S-hesperidin on Performance, Body Composition and Biochemicals Markers in Amateur Cyclists	N/A
Not yet recruiting	`NCT05990933` - Role of Adrenaline in in the Inflammatory Response in Diabetes	N/A
Not yet recruiting	`NCT06016023` - Evaluation of Macrophage Inflammatory Protein-1α as a Periodontal Disease Biomarker
Not yet recruiting	`NCT04608643` - Inflammatory Markers and Cbc Indices in Severely Malnourished Children
Recruiting	`NCT01934049` - Postoperative Recovery in Elderly Patients Undergoing Hip Hemi-arthroplasty	Phase 4
Recruiting	`NCT01417923` - The Immune and Clinical Impacts of Vitamin D in Patients With Chronic Musculo-skeletal Pain	Phase 4
Terminated	`NCT01377441` - Effect of Intravenous Ibuprofen on Inflammatory Responses in Patients Undergoing Surgery With General Anesthesia.	Phase 4
Completed	`NCT01301079` - Evaluation of the Effect of Ketamine on Remifentanil-induced Hyperalgesia	Phase 3
Terminated	`NCT00578578` - Trial to Study the Effects of Supplementary Omega-3 on Serum C-Reactive Protein Levels	Phase 4
Recruiting	`NCT04611334` - The Effects of HRV Biofeedback on Chronic Kidney Disease Patient.	N/A
Recruiting	`NCT03510702` - SCREENING OF EPIGENETIC BIOMARKERS (miRNAs) IN THE GINGIVAL SULCUS
Completed	`NCT03445234` - Blueberries, Bananas, Exercise Recovery	N/A
Not yet recruiting	`NCT05754294` - Electric Polarization of Red Blood Cells : A Cohort Study to Assess the Erythrocytes Membrane Integrity Through Charge Conservation, Following Cardiac Surgery.
Not yet recruiting	`NCT04386525` - Omega 3 and Ischemic Stroke; Fish Oil as an Option	Phase 4
Completed	`NCT04864600` - CANDLE - A Study of Acute Health Effects of Exposure to Particles Generated by Candles	N/A
Completed	`NCT04014439` - Relationship Between NLR and Prealbumin Levels With Diaphragm Thickness
Active, not recruiting	`NCT03002259` - Dexamethasone for Cardiac Surgery-II Trial	Phase 4