Joint Pain Clinical Trial
Official title:
Phase 2 Study Vitamin D3 Effects on Musculoskeletal Symptoms With Use of Aromatase Inhibitors
The Purpose of this study is to determine whether vitamin D3 supplements will decrease the muscle and bone pain that are reported by women who take Aromatase Inhibitors.
This project will determine the efficacy of vitamin D3 supplements for reducing side effects of treatment with aromatase inhibitors in women with a history of breast cancer that have no evidence of current disease. The aromatase inhibitors (AI) have become a critical component of adjuvant therapy for this population, but they cause bone pain, joint pain, joint stiffness, and muscle weakness in approximately 40% of patients. These symptoms, referred to as aromatase inhibitor-associated musculoskeletal symptoms (AIMSS), decrease quality of life and medication adherence. Identifying effective ways to decrease these symptoms may allow for longer and more adherent medication use and thus may improve disease-free survival. We hypothesize that vitamin D3 may decrease symptoms associated with the use of aromatase inhibitors. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT05052112 -
Cross-Over Study to Evaluate the Efficacy of E-PR-01 on Activity Induced Joint Pain
|
N/A | |
Recruiting |
NCT04285112 -
SPRINT: Signature for Pain Recovery IN Teens
|
||
Completed |
NCT04506411 -
Turmeric Efficacy for Mobility and Joint Function
|
N/A | |
Terminated |
NCT00973141 -
A Dose-ranging Study of the Safety and Effectiveness of JNJ-42160443 as add-on Treatment in Patients With Osteoarthritis-related Pain
|
Phase 2 | |
Completed |
NCT04408560 -
Evaluation of the Efficacy of a Homeopathic Protocol in Patients With Non-metastatic Breast Cancer
|
N/A | |
Completed |
NCT04150211 -
Effects of Exten(d) Supplementation on Training Ability in Recreational Runners
|
Phase 2 | |
Completed |
NCT03209895 -
Study to Evaluate the Safety and Efficacy of a Proprietary "Joint Health" Dietary Supplement in Subjects With Joint and Connective Tissue Pain
|
N/A | |
Withdrawn |
NCT01612728 -
Treatment for Joint Pains Due to Aromatase Inhibitor Therapy in Breast Cancer
|
Phase 2 | |
Completed |
NCT00691678 -
Glucosamine and Chondroitin for Aromatase Inhibitor Induced Joint Symptoms in Women With Breast Cancer
|
Phase 2 | |
Recruiting |
NCT05212259 -
Clinical Study to Evaluate the Effect of Different Doses of UC-II® Supplementation on the Range of Motion & Joint Discomfort in Healthy Subjects
|
N/A | |
Recruiting |
NCT04182659 -
Long Term Efficacy of Neuronavigation Guided rTMS in Alleviating Gulf War Illness Related Headaches and Pain Symptoms
|
N/A | |
Terminated |
NCT04712019 -
Evaluating Edema and Range of Motion Using Negative Pressure Therapy vs. Standard Surgical Dressing in Bilateral TKA
|
N/A | |
Recruiting |
NCT06074744 -
Subsartorial Nerve Block and Femoral Nerve Block in Total Knee Arthroplasty
|
N/A | |
Recruiting |
NCT00325845 -
Synvisc Injections for Lumbar Facet Joint Pain
|
Phase 3 | |
Terminated |
NCT04872556 -
Evaluation of the Effect of Laser Acupuncture on Taxane Acute Pain Syndrome Patients
|
N/A | |
Active, not recruiting |
NCT03865992 -
Curcumin in Reducing Joint Pain in Breast Cancer Survivors With Aromatase Inhibitor-Induced Joint Disease
|
N/A | |
Recruiting |
NCT05282992 -
NAtive Collagen Type II In Healthy VoluntEers With Joint Discomfort
|
N/A | |
Recruiting |
NCT04994249 -
Diagnostic and Prognostic Biomarkers for High-impact Chronic Pain: Development and Validation
|
||
Completed |
NCT04764110 -
Short-term Impact of Cyplexinol® on Self-reported Joint Pain
|
N/A | |
Not yet recruiting |
NCT06444867 -
A Study to Evaluate Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of LEO 158968
|
Phase 1 |