Intercostal Muscle Oxygenation During Exercise Tests

Muscle Oxygenation Clinical Trial

Official title:

Effect of Different Exercise Capacity Tests on Intercostal Muscle Oxygenation

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06410638
• Other study ID #: ICM_Moxy
• Status: Recruiting
• Start date: May 10, 2024
• Est. completion date: June 1, 2025

Study information

• Verified date: May 2024
• Source: Istanbul Medipol University Hospital
• Contact: ESRA PEHLIVAN
• Phone: 02164189616
• Email: fztesrakambur[@]yahoo.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The aim of our study is to determine the effects of different exercise capacity tests on intercostal muscle oxygenation and to reveal the effect of changing accessory respiratory muscle oxygenation on exercise test success.

Description:

In the study, intercostal muscle oxygenation will be measured in different exercise capacity tests. A total of 32 healthy young women and men between the ages of 18-25 who meet the inclusion criteria and voluntarily agree to participate in the study will be included in the study. The cases will be randomized into 2 groups: Six minute walking test group and incremental shuttle walking test group. Heart rate, oxygen saturation, and fatigue levels will be measured with the modified Borg scale before and after the tests. During the tests, oxygen levels of the intercostal muscles will be monitored with the MOXY device. After sufficient wash out time, the groups will be crossed and different exercise tests will be applied to the cases. The result of our study will provide information about the use of intercostal muscles during different exercise tests. As a result of the study, results that can be interpreted for patient groups with circulatory system, respiratory system and physical limitations will be obtained.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 32
• Est. completion date: June 1, 2025
• Est. primary completion date: June 1, 2025
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• Being between the ages of 18-35
• Body Mass Index <25 kg/m²
• Participating in the study voluntarily

Exclusion Criteria:

• Being a smoker
• Presence of any systemic, orthopedic or cardiopulmonary disease that may prevent exercise tests
• Presence of any diagnosed respiratory, vascular and heart disease

Related Conditions & MeSH terms

• Muscle Oxygenation

Intervention

Diagnostic Test:
• Six Minute Walking Test
It is applied in a 30 m long corridor in an indoor environment, and the distance walked by the patient in a six-minute period, oxygen saturation, heart rate, and change in dyspnea are recorded. For this, before starting the test, oxygen saturation, heart rate, arterial blood pressure and dyspnea level according to the Borg scale are recorded. The same parameters are measured again at the end of the test. The feature of this test is that the person walks at his own pace, stopping when necessary and allowing the use of oxygen. It is an exercise test that is easy to perform and well tolerated.
• Shuttle walking test
Shuttle walking test at increasing speed is an exercise test in which walk between two cones 10 m apart at an increasing speed throughout the test and each 10-meter journey between the two cones is counted as a shuttle.

Locations

Country	Name	City	State
Turkey	University of Health Sciences Turkey	Istanbul

Sponsors (1)

Lead Sponsor	Collaborator
Istanbul Medipol University Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Evaluation of Muscle Oxygenation of intercostal muscles	The measurement will be made with the MOXY device. The device will be placed on the intercostal muscle and measurements will be taken during the exercise tests. Measured values at the beginning, end and every 1 minute will be taken and analyzed.	During intervention
Secondary	Forced expiratory pressure in one second	It will be performed with Cosmed Pony Fx (Italy) desktop spirometry device.	Baseline
Secondary	Evaluation of blood pressure	Sistolik and diastolic blood pressure will be measured with the Wrist Blood Pressure Monitor	During the intervention
Secondary	Evaluation of heart rate	It will be measured with a pulse oximeter.	During the intervention
Secondary	Evaluation of oxygen saturation	It will be measured with a pulse oximeter.	During the intervention
Secondary	Forced vital capacity	It will be performed with Cosmed Pony Fx (Italy) desktop spirometry device.	Baseline