The Effects of Resistance Training and Protein Supplementation in Healthy Elderly Men and Women.

Muscle Loss in Elderly Clinical Trial

Official title:

The Effects of Resistance Type Exercise Training and Protein Supplementation on Skeletal Muscle Mass, Strength, and Muscle Characteristics in Healthy Elderly Men and Women

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01004588
• Other study ID #: MEC 09-3-056
• Status: Completed
• Phase: N/A
• First received: October 26, 2009
• Last updated: April 9, 2015
• Start date: November 2009
• Est. completion date: November 2012

Study information

• Verified date: April 2015
• Source: Maastricht University Medical Center
• Contact: n/a
• Is FDA regulated: No
• Health authority: Netherlands: The Central Committee on Research Involving Human Subjects (CCMO)
• Study type: Interventional

Clinical Trial Summary

The main objective of this study is to examine the effects of resistance type exercise training combined with nutritional support on body composition and muscle characteristics in healthy elderly men and women. For a comprehensive insight into the potential underlying mechanisms of the intervention effects on whole body-, muscle- and myocellular level, a broad range of tests will be performed before, during, and after the intervention period.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: November 2012
• Est. primary completion date: November 2012
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 65 Years to 90 Years

Eligibility

Inclusion Criteria:

• over 65 years

• healthy men and women

Exclusion Criteria:

• cardiovascular disease

• COPD

• Parkinson

• rheumatoid arthritis

• musculoskeletal/orthopaedic disorders

• cognitive impairment

• subjects with metal implants

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Muscle Loss in Elderly

Intervention

Dietary Supplement:
• Protein drink
total of 15 g protein/d in a protein drink consumed every morning after breakfast during 24 weeks
• placebo drink
subjects consume a placebo drink every morning after breakfast over a period of 24 weeks.

Locations

Country	Name	City	State
Netherlands	Maastricht University	Maastricht

Sponsors (2)

Lead Sponsor	Collaborator
Maastricht University Medical Center	Top Institute Food and Nutrition

Country where clinical trial is conducted

Netherlands, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in muscle mass measured by DXA-scan and CT-scan		0, 12 and 24 weeks	No