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Acute Physiological Responses to Twice Daily Blood Flow Restriction Training

Muscle Weakness Clinical Trial

Official title:
Effects of Twice Daily Blood Flow Restriction Training on Muscle Swelling, Markers of Exercise Induced Muscle Damage and Inflammation: A Randomised Control Trial

Clinical Trial Summary

The Academic Department of Military Rehabilitation (ADMR) is currently conducting a pan-defence, randomised control trial (RCT) investigating the utility of twice daily blood flow restriction training in UK military personnel with persistent knee pain (NCT05719922). Due to logistical confinements, this pan-defence RCT is confined to collecting outcome data pre and post-intervention. Therefore, the acute physiological mechanisms which underpin adaptation will remain unknown. Consequently, ADMR is undertaking an additional, single centre RCT which will compare the acute physiological responses to low load resistance training with and without the addition of blood flow restriction. Specifically, this study will elucidate the effect of twice daily blood flow restriction training on measures of muscle swelling, muscle damage and inflammation. This data may aid in the optimisation of blood flow restriction exercise prescription within UK Defence Rehabilitation and elsewhere.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06334224
Study type Interventional
Source Defence Medical Rehabilitation Centre, UK
Contact Peter Ladlow, PhD
Phone +44 (0)1509 251 500
Email peter.ladlow100@mod.gov.uk
Status Recruiting
Phase N/A
Start date November 6, 2023
Completion date September 2024
View Details
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