Effect of Strength Versus Endurance Training on Muscle Damage in Gym Athletes on Caffeine Supplementation.

Muscle Damage Clinical Trial

Official title:

Effect of Strength Versus Endurance Training on Muscle Damage in Gym Athletes on Caffeine Supplementation.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06086691
• Other study ID #: REC/01241 Mian Waleed Ahmed
• Status: Completed
• Phase: N/A
• Start date: January 12, 2022
• Est. completion date: January 31, 2023

Study information

• Verified date: November 2023
• Source: Riphah International University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Dietary supplements to enhance exercise and athletic performance come in a variety of forms, including tablets, capsules, liquids, powders, and bars. Many of these products contain numerous ingredients in varied combinations and amounts. Among the more common ingredients are amino acids, protein, creatine, and caffeine

Description:

Caffeine is a popular nutritional supplement among gym athletes. It is frequently used as an ergogenic aid to improve physical performance, delay fatigue, and increase muscle power. This research aims to evaluate the effectiveness of caffeine through the blood sample test (Serum CK, LDH levels, AST levels) on muscle damage of gym athletes who are performing aerobic and strength training. This study would help understand the effects of strength training and endurance training on muscle damage in gym athletes who are consuming caffeine and to check the serum enzymes level of both groups who are on strength training and those who are on endurance level training, therefore, this study would help determine which athletes should be careful while consuming caffeine for a particular exercise regimen

Recruitment information / eligibility

• Status: Completed
• Enrollment: 14
• Est. completion date: January 31, 2023
• Est. primary completion date: November 30, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• Male gym athletes
• Age: 18-40 years
• Athletes with at least three days training session per week

Exclusion Criteria:

• Athletes already on caffeine supplementation
• Athletes with above normal serum enzyme levels

Related Conditions & MeSH terms

• Muscle Damage

Intervention

Other:
• Strength Training with Caffeine
The intervention protocol consists of 5 types of strength training exercises. The following exercises will be performed for the strength training group: bench press (3 sets of 10 reps) biceps curl (3 sets of 10 reps) triceps pushdown (3 sets of 10 reps) leg press (3 sets of 10 reps) leg extension (3 sets of 10 reps) Strength training would be performed in 3 sets of 10 repetitions with 2 minutes of rest between each exercise. This protocol will be performed in a 30-40-minute session. 10-15 minutes of light warm-up activities will be performed before the start of each exercise session. The intervention sessions would be carried out with a 3-5-day gap between the two intervention sessions.
• Endurance Training with Caffeine
The intervention protocol consists of 3 types of endurance training exercises. The following exercises will be performed by this group: Cycling (15 min) Running (20 min) Rowing (10 min) The intervention sessions would be carried out with a 3-5-day gap between the two intervention sessions.

Locations

Country	Name	City	State
Pakistan	Riphah International University (RIU)	Islamabad	Islamabad Capital Territory

Sponsors (1)

Lead Sponsor	Collaborator
Riphah International University

Country where clinical trial is conducted

Pakistan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Serum CK Levels	Serum CK level is the amount of an enzyme called creatine kinase (CK) in the blood. CK is a type of protein present in the muscle cells in human body need which is essential for proper functioning. Levels of CK can rise after a heart attack, skeletal muscle injury, or strenuous exercise	Pre-intervention, after 24 hours of the intervention, after 3 days before second intervention, and after 24 hours of the second intervention
Primary	Serum LDH levels	Lactate Dehydrogenase (LDH) is enzyme found in almost every cell of the human body, including your blood, muscles, brain, kidneys, and pancreas.	Pre-intervention, after 24 hours of the intervention, after 3 days before second intervention, and after 24 hours of the second intervention
Primary	Serum AST levels	Aspartate aminotransferase (AST) are enzymes found mainly in the liver, but also found in red blood cells, heart cells, muscle tissue and other organs, such as the pancreas and kidneys.	Pre-intervention, after 24 hours of the intervention, after 3 days before second intervention, and after 24 hours of the second intervention
Secondary	Rating of fatigue scale/Numeric Rating Scale-Fatigue	This rating-of-fatigue (ROF) scale has been developed which can track the intensity of perceived fatigue in a variety of contexts.	Pre-intervention, after 24 hours of the intervention, after 3 days before second intervention, and after 24 hours of the second intervention