Muscle Damage Clinical Trial
Official title:
Comparison of the Effect of Whey and Soy Protein Supplementation on Muscle Damage Markers and Performance After a Speed Endurance Training Protocol in Football Players
Verified date | November 2020 |
Source | University of Thessaly |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
In a constant effort to find ways to make a quicker recovery between demanding workouts and football matches, this study is the first to investigate the benefits of protein supplementation, and compares two types of proteins, an animal-derived (whey) and a plant-derived (soy) protein, after an exercise-induced muscle injury caused by a speed endurance training protocol. Soy protein could be a cheaper and more environment-friendly alternative for athletes involved in high-velocity strength training.
Status | Completed |
Enrollment | 10 |
Est. completion date | February 20, 2019 |
Est. primary completion date | January 20, 2019 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Male |
Age group | 18 Years to 25 Years |
Eligibility | Inclusion Criteria: - Playing at a competitive level (top three divisions) for =3 years - Free of any recent history of illnesses, musculoskeletal problems and metabolic diseases - No use of supplements and medications (for =6 months prior to the study) - Non-smokers Exclusion Criteria: - A known milk intolerance or allergy - A recent febrile illness - History of muscle lesion - Lower limb trauma - Metabolic diseases. |
Country | Name | City | State |
---|---|---|---|
Greece | Exercise Biochemistry Laboratory, School of Physical Education & Sports Sciences, University of Thessaly | Tríkala |
Lead Sponsor | Collaborator |
---|---|
University of Thessaly |
Greece,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in field activity during the speed-endurance production training (SEPT) | Field activity will be continuously recorded during both SEPT sessions using global positioning system (GPS) technology | Throughout the SEPT sessions in all trials | |
Primary | Change in heart rate during the speed-endurance production training (SEPT) | Heart rate will be continuously recorded during both SEPT sessions using heart rate monitors. | Throughout the SEPT sessions in all trials | |
Primary | Change in creatine kinase in plasma | Concentration of creatine kinase will be measured in plasma | Baseline; Post-loading (Day 7); 24 hours (Day 9) and 48 hours (Day 10) following SEPT session 1. | |
Primary | Change in repeated sprint ability (RSA) | 5 x 30 m sprints will be performed with 25 seconds rest in-between | Baseline; Post-loading (Day 7); 24 hours (Day 9) following SEPT session 1 | |
Primary | Change in countermovement jump (jump height in centimeters) | Countermovement jump will be assessed on a contact platform | Baseline; Post-loading (Day 7); 24 hours (Day 9) following SEPT session 1 | |
Primary | Change in isokinetic strength of lower limbs | Isokinetic strength will be assessed on an isokinetic dynamometer for both knee extensors and knee flexors at 60 degrees. | Baseline; Post-loading (Day 7); 24 hours (Day 9) following SEPT session 1 | |
Primary | Change in maximal voluntary isometric contraction (MVIC) of lower limbs | MVIC will be assessed on an isokinetic dynamometer for knee extensors at 90 degrees and knee flexors at 30 degrees | Baseline; Post-loading (Day 7); 1, 2 and 3 hours post-SEPT session 1; 24 hours (Day 9) and 48 hours (Day 10) following SEPT session 1. | |
Primary | Change in delayed onset of muscle soreness | Muscle soreness will assessed during palpation of the muscle belly and the distal region of relaxed vastus medialis, vastus lateralis and rectus femoris following three repetitions of of a full squat. Subjects will rate their DOMS on a visual analogue scale (0-10). A score of O indicates no sign or symptom of DOMS, a score of 10 indicated severe signs and symptoms of delayed onset muscle soreness (DOMS). These signs and symptoms include dull, diffuse pain and tenderness; stiffness; swelling; and decreased strength of the exercised muscle. | Baseline; Post-loading (Day 7); 24 hours (Day 9) and 48 hours (Day 10) following SEPT session 1. | |
Primary | Change in total antioxidant capacity in plasma | Total antioxidant capacity will be measured in plasma | Baseline; Post-loading (Day 7); 24 hours (Day 9) and 48 hours (Day 10) following SEPT session 1. | |
Primary | Change in protein carbonyl levels in plasma | Protein carbonyl levels will be measured in plasma | Baseline; Post-loading (Day 7); 24 hours (Day 9) and 48 hours (Day 10) following SEPT session 1. | |
Primary | Change in GSH levels in red blood cell lysate | GSH will be measured in red blood cell lysate | Baseline; Post-loading (Day 7); 24 hours (Day 9) and 48 hours (Day 10) following SEPT session 1. | |
Primary | Change in sprint time | Sprint time will be assessed over a 10m and 30m distance using light cells. | Baseline; Post-loading (Day 7); 24 hours (Day 9) following SEPT session 1 | |
Secondary | Dietary intake | Dietary intake will be assessed using 7-day diet recalls. | Over a 7-day period at baseline. | |
Secondary | Concentration of blood lactate | Blood lactate will be measured using an automatic analyzer | Pre- and Post-SEPT session 1 (Day 8), Pre- and Post-SEPT session 2 (Day 10) | |
Secondary | Change in habitual physical activity | Physical activity will be measured using 3-axial accelerometers | Over a 7-day period at baseline | |
Secondary | Change in resting metabolic rate (RMR) | RMR will be measured using open-circuit indirect calorimeter with a ventilated hood system, after an overnight fast. | At baseline. | |
Secondary | Change in body composition | Body composition will be assessed using dual-energy X-ray absorptiometry (DXA). | At baseline. | |
Secondary | Change in maximal oxygen uptake | Maximal oxygen uptake (VO2max) will be measured during a graded exercise testing on a treadmill, by using open-circuit spirometry with an automated online pulmonary gas exchange system, via breath-by-breath analysis. | At baseline. | |
Secondary | Change in soccer-specific conditioning. | Soccer-specific conditioning will be assessed using the the Yo-Yo intermittent endurance level 2 test (Yo-Yo IE2) and the Yo-Yo intermittent recovery level 2 test (Yo-Yo IR2). | At baseline. |
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