Muscle Damage Clinical Trial
Official title:
The Effects of Made-To-Measure Compression Garments on the Recovery of Performance and Markers of Muscle Damage and Inflammation in Elite Modern Pentathletes
Aims To assess the efficacy of made to measure, high pressure compression garments (CG) for
facilitating the recovery of strength, muscular power, and physiological markers of muscle
damage following fencing, when compared a sham treatment
Rationale for study design
The results of a recent meta-analysis have informed the design of this study. The conclusions
of the meta-analysis were that CG are most effective for the recovery of:
- Force and power performance following eccentric/plyometric exercise
- Maximal force production, at least 24 hours post-exercise (for example in strength and
power athletes undertaking resistance training programmes)
- Additionally, the recovery of high-intensity cardiovascular performance may also be
enhanced by the used of CG, when tested 24 hours following exercise which incurs
metabolic stress Accordingly, the current study was designed to investigate the effects
of CG of intense, competitive sparring following fencing sessions, held at the British
Modern Pentathlon training base at the University of Bath.
Status | Recruiting |
Enrollment | 10 |
Est. completion date | February 28, 2019 |
Est. primary completion date | December 31, 2018 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 40 Years |
Eligibility |
Inclusion Criteria: - Athletes must be full-time athletes over the age of 18 - Training regularly for at least 3 months without extended disruption to training (> 2 weeks) Exclusion Criteria: - Presentation of injuries or chronic illnesses - Inactivity or disruptions to training > 2 weeks (e.g. due to injury) - The use of anti-inflammatory medications - Over 40 years old (classification as a "Masters" athlete) |
Country | Name | City | State |
---|---|---|---|
United Kingdom | University of Bath | Bath | Somerset |
United Kingdom | St Marys University | London |
Lead Sponsor | Collaborator |
---|---|
St Mary's University College | Modern Pentathlon GB |
United Kingdom,
Brophy-Williams N, Driller M, Halson S, Fell J, Shing C. Evaluating the Kikuhime pressure monitor for use with sports compression clothing. Sports Engineering. 2014;17(1):55-60
Brown F, Gissane C, Howatson G, van Someren K, Pedlar C, Hill J. Compression Garments and Recovery from Exercise: A Meta-Analysis. Sports Med. 2017 Nov;47(11):2245-2267. doi: 10.1007/s40279-017-0728-9. Review. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Maximal isometric voluntary contraction strength for knee extension (change in Newtons compared to baseline) | Participants will be assessed for strength performance with maximal isometric voluntary contraction of the knee extensors (using a strain gauge) at the following time-points after fencing and compared to baseline: Immediately post, 12 hours post, 36 hours post-fencing (x 2 - crossover). | 36 h. Second leg will be conducted after 1 week "washout" (10 days in total) | |
Primary | Lower body reactive strength (jump height/contact time in m/s) following a drop from a 0.6 m box onto a force plate (change in m/s compared to baseline) | Participants will be compared to baseline for reactive strength performance at the following time-points after fencing:Immediately post, 12 hours post, 36 hours post-fencing (x 2 - crossover). Jump height (m) and contact time (s) will be recorded following a drop from a 0.6 m box onto a force-plate. |
36 h. Second leg will be conducted after 1 week "washout" (10 days in total) | |
Primary | 3200 m run time trial performance (change in seconds compared to baseline) | Participants will be timed for 3200 m running performance at the following time-points after fencing and compared to baseline: Immediately post, 12 hours post, 36 hours post-fencing (x 2 - crossover). | 36 h. Second leg will be conducted after 1 week "washout" (10 days in total) | |
Secondary | Perceived soreness, scored by drawing a vertical line on a 200 mm visual analogue scale from 0 mm (no soreness) to 200 mm (worst soreness imaginable). Change in mm will be compared to baseline. | Participants will be measured for muscular soreness at the following time-points after fencing and compared to baseline: Immediately post, 12 hours post, 36 hours post-fencing (x 2 - crossover). Perceived soreness will be scored by drawing a vertical line on a 200 mm visual analogue scale from 0 mm (no soreness) to 200 mm (worst soreness imaginable) and compared to baseline. | 36 h. Second leg will be conducted after 1 week "washout" (10 days in total) | |
Secondary | Circulating creatine kinase concentrations (CK - change in international units compared to baseline) | Participants will be measured for circulating creatine kinase concentrations (CK) at the following time-points after fencing and compared to baseline: Immediately post, 12 hours post, 36 hours post-fencing (x 2 - crossover). Change from baseline will be measured in international units (IU) | 36 h. Second leg will be conducted after 1 week "washout" (10 days in total) | |
Secondary | Mid-thigh girth (MTG) at the mid-thigh skinfold site as defined by International Society of Anthropometry and Kinanthropometry. Change will be measured in mm by comparing to baseline | Thigh circumference (mm) at the mid-thigh skinfold site (as defined by International Society of Anthropoemtry and Kinanthropometry) will be measured at the following time-points after fencing and compared to baseline: Immediately post, 12 hours post, 36 hours post-fencing (x 2 - crossover). | 36 h. Second leg will be conducted after 1 week "washout" (10 days in total) | |
Secondary | Free oxygen radicals defense (FORD) status (change in mmol/L Trolox equivalents compared to baseline) | Blood free oxygen radicals defense (FORD) will be measured from capillary samples taken from the earlobe at the following time-points after fencing and compared to baseline: Immediately post, 12 hours post, 36 hours post-fencing (x 2 - crossover). | 36 h. Second leg will be conducted after 1 week "washout" (10 days in total) | |
Secondary | Free oxygen radicals (FORT) status (change in mmol/L H2O2 equivalents compared to baseline) | Blood free oxygen radicals (FORT) will be measured from capillary samples taken from the earlobe at the following time-points after fencing and compared to baseline: Immediately post, 12 hours post, 36 hours post-fencing (x 2 - crossover). | 36 h. Second leg will be conducted after 1 week "washout" (10 days in total) |
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