Comprehensive Swallowing Rehabilitation in Patients With MSA

Status Recruiting

Clinical Trial Summary

The purpose of this study is to investigate the effect of comprehensive swallowing rehabilitation in patients with multiple system atrophy.

Clinical Trial Description

Multiple system atrophy (MSA) is a rapidly progressive neurodegenerative disease characterized by parkinsonism, cerebellar syndrome, and autonomic failure. Dysphagia is a clinically significant symptom leading to pneumonia that causes death in patients with MSA. Although the symptoms of dysphagia in the two subtypes of MSA-the parkinsonian variant and the cerebellar variant- are different, there is no significant difference in the latency to onset of tube feeding. Therefore, effective intervention is needed to improve the safety and efficiency of swallowing regardless of the subtypes of MSA. Although swallowing rehabilitation has been widely applied for swallowing disorders in patients with MSA, few studies have reported the clinical effect of applying swallowing therapy. Comprehensive swallowing rehabilitation has focused on functional muscle training, compensatory swallowing maneuvers, and thermal-tactile stimulation, which is used to treat dysphagia from stroke, Parkinson's disease, and head and neck cancer. Therefore, this study aims to investigate the effect of comprehensive swallowing rehabilitation in patients with MSA. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04782284
Study type	Interventional
Source	Seoul National University Hospital
Contact	Han Gil Seo, MD, PhD
Phone	82-2-2072-1659
Email	hgseo80@gmail.com
Status	Recruiting
Phase	N/A
Start date	May 17, 2021
Completion date	December 30, 2024

View Details

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