Pulmonary Nodule, Solitary Clinical Trial
Official title:
GE Healthcare VolumeRAD Lung Nodule Detection Study
To perform a multiple reader, multiple case (MRMC) observer study assessing the detection performance of VolumeRAD tomosynthesis of the chest in detecting lung nodules.
Digital tomosynthesis is a form of limited angle tomography that creates a series of section
images using a conventional x-ray tube and generator, a digital detector, and appropriate
reconstruction software. It creates section images from a series of projection images
acquired as the x-ray tube moves along a prescribed path. Because tomosynthesis can minimize
the visual presence of overlying anatomy - the ribs, for example - it has the potential to
improve the detection of lesions such as pulmonary nodules when compared with conventional
chest radiography.
The primary aim of this study is to determine whether the use of VolumeRAD tomosynthesis, in
addition to CxR, increases physician accuracy in the detection of lung nodules between 3mm
and 20mm in diameter when compared to conventional posterior-anterior (PA) and lateral (LAT)
chest radiography (CxR). This aim will be addressed by measuring free-response performance
of experienced (with VolumeRAD), blinded expert readers' detection performance.
Specifically, we will compare detection performance, as measured by the area under the
alternative free response receiver operating characteristic (AFROC) curve, among readers
viewing PA and LAT chest X-rays versus VolumeRAD tomosynthesis. The nodule will be the unit
of analysis.
;
Observational Model: Case-Only, Time Perspective: Cross-Sectional
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03649906 -
A Clinical Study of Optimized CT-guided Pulmonary Nodule Microcoil Localization Technique
|
N/A | |
Completed |
NCT05963945 -
Multi-Reader Retrospective Study Examining Carebot AI CXR 2.0.21-v2.01 Implementation in Everyday Radiology Clinical Practice
|
||
Completed |
NCT04066699 -
Percutaneous Localization: Open-label Registry of Thoracic Surgery
|
||
Not yet recruiting |
NCT05477251 -
Comparative Study on the Efficacy and Safety of Microwave Ablation and Lobectomy in the Treatment of Ground Glass Nodules Located in the Pulmonary Hilar Region
|
N/A | |
Completed |
NCT03591445 -
Is Bronchoscopy Necessary in the Preoperative Workup of GGO Lung Cancer?(ECTOP-1005)
|
N/A | |
Withdrawn |
NCT04894682 -
Safety and Long-term Effects of COVID-19 Vaccines in Patients With Pulmonary Tumor
|
||
Recruiting |
NCT03790735 -
The MDA Test to Differentiate of Benign and Malignant Pulmonary Nodules
|
||
Active, not recruiting |
NCT03992183 -
Utility of CAML as Diagnostic for Early Stage Lung Cancer
|
||
Recruiting |
NCT04552054 -
Mixed Reality Technique Combined With 3D Printing Navigational Template for Localizing Pulmonary Nodules
|
N/A | |
Recruiting |
NCT05389774 -
DOLCE: Determining the Impact of Optellum's Lung Cancer Prediction Solution
|
||
Recruiting |
NCT06308120 -
A Trial to Compare Robotic Assisted Bronchoscopy Ion's Clinical Utility for Peripheral Lung Nodule Access and Diagnosis to ENB
|
N/A | |
Completed |
NCT04209972 -
The Benefit of UHR-CT: Precision of Repeated Volume Measurements of Pulmonary Nodules
|
N/A | |
Completed |
NCT03181490 -
Circulating Tumor DNA Methylation Test to Differentiate Benign and Malignant Pulmonary Nodules
|
||
Recruiting |
NCT05445635 -
Added Value of a Small Camera (Iriscope) in the Endoscopic Diagnosis of Peripheral Lung Nodules and Masses
|
N/A | |
Recruiting |
NCT04270799 -
Lung Nodule Imaging Biobank for Radiomics and AI Research
|
||
Recruiting |
NCT00841750 -
Chest Tube After a Video-assisted Thoracoscopic Surgery Pulmonary Wedge Resection
|
Phase 3 | |
Recruiting |
NCT06426628 -
Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier
|
||
Recruiting |
NCT05415670 -
Benign/Malignant Pulmonary Nodule Classification Based on High-throughput Whole-genome Methylation Sequencing(GM-seq)
|
||
Recruiting |
NCT04005677 -
The Early Diagnosis of Pulmonary Nodule Based on Multi-dimension Messages
|
||
Recruiting |
NCT05968898 -
Assessment of a Radiomics-based Computer-Aided Diagnosis Tool for Pulmonary nodulES
|
N/A |