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Clinical Trial Summary

A Phase Ⅱ Clinical Study Evaluating the Efficacy and Safety of Human BCMA Targeted T Cells Injection(BCMA CAR-T) Therapy for R/R MM. Patients will be given a conditioning chemotherapy regimen of fludarabine and cyclophosphamide followed by a single infusion of BCMA CAR+ T cells.


Clinical Trial Description

Participants with relapsed/refractory multiple myeloma can participate if all eligibility criteria are met. Tests required to determine eligibility include disease assessments, a physical exam, Electrocardiograph, Computedtomography (CT)/Magnetic Resonance Imaging(MRI)/Positron Emission Tomography(PET), and blood draws. Participants receive chemotherapy prior to the infusion of BCMA CAR+ T cells. After the infusion, participants will be followed for side effects and effect of BCMA CAR+ T cells. Study procedures may be performed while hospitalized. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05594797
Study type Interventional
Source Hrain Biotechnology Co., Ltd.
Contact Xuedong Sun, M.D.
Phone +8615811287219
Email sunxuedong@dashengbio.com
Status Recruiting
Phase Phase 2
Start date July 12, 2022
Completion date July 31, 2027

See also
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