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Clinical Trial Summary

This study will evaluate efficacy and tolerability of iberdomide, bortezomib, dexamethasone and isatuximab on demand administered in combination.


Clinical Trial Description

This is a phase II, multicenter, single arm, response adapted, open label study of iberdomide, weekly bortezomib and dexamethasone (IberBd) for upfront treatment of transplant ineligible patients with Multiple Myeloma. Isatuximab will be added to treatment regimen for those who do not attain VGPR after 4 cycles or MRD negativity at 4 cycles of IberBd. This study will have an Induction phase (cycle 1-4), an Intensification phase (cycle 5-8) and a Maintenance phase (cycle 9 onwards). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05272826
Study type Interventional
Source Canadian Myeloma Research Group
Contact Aniba Khan
Phone 4164779849
Email cmrg@cmrg.ca
Status Not yet recruiting
Phase Phase 2
Start date October 2024
Completion date March 2031

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