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Clinical Trial Summary

This is a global, open-label, multi-arm, multi-cohort, multi-center, phase 1/2 study to determine the safety, tolerability, efficacy, PK of bb2121 in combination with other therapies in adult subjects with R/RMM. The following combinations will be - Arm A will test bb2121 in combination with CC-220 (± low-dose dexamethasone) - Arm B will test bb2121 in combination with BMS-986405 (JSMD194) Combination agents being tested may be administered before, concurrently with and/or following (ie, maintenance) bb2121 infusion. The study will consist of 2 parts: dose finding (Phase 1) and dose expansion (Phase 2). Dose expansion may occur in one or more arms.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04855136
Study type Interventional
Source Celgene
Contact
Status Active, not recruiting
Phase Phase 1/Phase 2
Start date June 1, 2021
Completion date December 6, 2026

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