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A Nationwide Phase 2 Trial of Patients With Smoldering and Active Multiple Myeloma (MM) — iStopMM  

Multiple Myeloma Clinical Trial

Official title:
Iceland Screens Treats or Prevents Multiple Myeloma (iStopMM): A Nationwide Phase 2 Trial of Patients With Smoldering and Active Multiple Myeloma (MM)

Clinical Trial Summary

The purpose of this study is to determine the efficacy of treating patients with intermediate risk smoldering multiple myeloma (SMM) with combinational therapy with dexamethasone and lenalidomide (Rd) and patients with high risk SMM with combinational therapy with Rd and carfilzomib.

Clinical Trial Description

This is an open label, single center, phase II study assessing the efficacy of treating patients with intermediate-risk smoldering myeloma (SMM) with combinational therapy with dexamethasone and lenalidomide and treating patients with high risk SMM and active multiple myeloma (MM) with combinational therapy with dexamethasone, lenalidomide and carfilzomib. Patients that are eligible for this study are participants in the IstopMM study (ClinicalTrials.gov number, NCT03327597) that are diagnosed with intermediate or high-risk SMM or active MM. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03815279
Study type Interventional
Source Landspitali University Hospital
Contact
Status Enrolling by invitation
Phase Phase 2
Start date June 24, 2019
Completion date January 2028
View Details
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