Multiple Myeloma Clinical Trial
Official title:
Carfilzomib, Lenalidomide, and Dexamethasone in Newly-Diagnosed Multiple Myeloma: A Clinical and Correlative Phase I/II Dose Escalation Study
The purpose of this study is to test whether giving high doses of carfilzomib along with the other drugs (lenalidomide and dexamethasone) is safe and which dose is best tolerated by patients. In addition, the study is designed to test the amount of remaining myeloma cells in the body after treatment with higher carfilzomib doses which is known as minimal residual disease (MRD).
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| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
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Phase 1 | |
| Completed |
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Once-weekly Versus Twice-weekly Carfilzomib in Combination With Dexamethasone in Adults With Relapsed and Refractory Multiple Myeloma
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Phase 3 | |
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Phase 1/Phase 2 | |
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Phase 3 | |
| Active, not recruiting |
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Phase 1 | |
| Recruiting |
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The Safety and Efficay Investigation of CAR-T Cell Therapy for Patients With Hematological Malignancies
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N/A | |
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Phase 3 | |
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Phase 2 | |
| Completed |
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Myeloid-Derived Suppressor Cells and Checkpoint Immune Regulators' Expression in Allogeneic SCT Using FluBuATG
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Phase 1 | |
| Recruiting |
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|
Phase 2 | |
| Completed |
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First-in- Human Imaging of Multiple Myeloma Using 89Zr-DFO-daratumumab, a CD38-targeting Monoclonal Antibody
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Phase 1/Phase 2 | |
| Terminated |
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NY-ESO-1-redirected CRISPR (TCRendo and PD1) Edited T Cells (NYCE T Cells)
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Phase 1 | |
| Completed |
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Phase 1/Phase 2 | |
| Active, not recruiting |
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Phase 1 | |
| Active, not recruiting |
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Phase 2 | |
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|
Phase 1/Phase 2 | |
| Withdrawn |
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|
Phase 2 | |
| Recruiting |
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Phase 1 | |
| Completed |
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CART-BCMA Cells for Multiple Myeloma
|
Phase 1 |