Use of Chamomilla Recutita in Mucositis

Status Completed

Clinical Trial Summary

To determine the Chamomilla recutita solution dose needed to reduce the intensity and evolution time of oral mucositis in adult subjects submitted to HSCT.

Clinical Trial Description

Population: adult subjects, submitted to hematopoietic stem cell transplantation (HSCT) at a cancer hospital in the interior of São Paulo State. The following inclusion criteria were adopted for sample selection purposes: subjects over 18 years of age, candidates for allogeneic HSCT and with intact oral cavity on the first day of conditioning. Subjects will be excluded if they present any adverse reaction to the active principles of Chamomilla recutita; receive oral or intravenous anticoagulation therapy; use oral or systemic topical anti-inflammatory medication; receive any other type of intervention for mucositis not included in the standard oral care protocol. ;

Study Design

Related Conditions & MeSH terms

Mucositis

Clinical Trial Details

NCT number	NCT01341054
Study type	Interventional
Source	University of Sao Paulo
Contact
Status	Completed
Phase	N/A
Start date	January 2011
Completion date	August 2011

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02252926` - Local Anesthetic Treatment of Oral Pain in Patients With Mucositis	Phase 2
Completed	`NCT01155609` - L-lysine in Treating Oral Mucositis in Patients Undergoing Radiation Therapy With or Without Chemotherapy For Head and Neck Cancer	N/A
Completed	`NCT00357942` - Topical Morphine for Stomatitis-related Pain Induced by Chemotherapy	Phase 4
Completed	`NCT00360685` - Tacrolimus and Mycophenolate Mofetil (MMF) in GVHD Prophylactic Regimen Compared to Tacrolimus and Methotrexate (MTX	N/A
Completed	`NCT04586491` - The Effect of Oral Care Protocol on Prevention of Oral Mucositis in Pediatric Cancer Patients	N/A
Withdrawn	`NCT02589860` - Analysis of Oral Mucositis in Patient's Undergoing Melphalan Conditioning and Autologous Stem Cell Transplant
Not yet recruiting	`NCT02506231` - The Effect of Folinic Acid Rescue Following MTX GVHD Prophylaxis on Regimen Related Toxicity and Transplantation Outcome	Phase 2/Phase 3
Completed	`NCT02605382` - Efficacy of 0.12% Chlorhexidine Gluconate for Peri-implant Mucositis	Phase 2
Completed	`NCT02639377` - Efficacy of 0.12% Chlorhexidine Gluconate for Peri-implant Mucositis and Gingivitis	Phase 2
Terminated	`NCT02575313` - The Effects of Whole Food Intervention on Mucositis in Patients Treated for Head and Neck Cancer	Phase 1/Phase 2
Completed	`NCT00956254` - Fentanyl Sublingual Spray in Treating Opioid-tolerant Cancer Patients With or Without Oral Mucositis	Phase 3
Completed	`NCT00584597` - A Trial of Homeopathic Medication TRAUMEEL S for the Treatment of Radiation-Induced Mucositis	Phase 1
Enrolling by invitation	`NCT05590117` - Protective Effect of Pentoxifylline Against Chemotherapy Induced Toxicities in Patients With Colorectal Cancer	Early Phase 1
Completed	`NCT05635929` - Oral Mucositis and Quality of Life With a Mucosa Topical Composition in Head & Neck Cancer Patients.	N/A
Completed	`NCT05181943` - Effectiveness of Photo-biomodulation in the Treatment of Chemotherapy Induced Mucositis	N/A
Completed	`NCT03713567` - Clinical, Immunological and Microbiological Evaluation of Experimental Gingivitis and Peri-implant Mucositis	N/A
Completed	`NCT02671812` - Outcome After Dental Implant Treatment
Terminated	`NCT02273752` - Pharmacokinetically Guided Everolimus in Patients With Breast Cancer, Pancreatic Neuroendocrine Tumors, or Kidney Cancer	Phase 2
Recruiting	`NCT01707641` - Effect of Lactobacillus Brevis CD2 in Prevention of Radio-chemotherapy Induced Oral Mucositis in Head and Neck Cancer	Phase 4
Completed	`NCT01015183` - Prevention Chemotherapy Induced Mucositis by Zinc Sulfate	Phase 2/Phase 3