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Treatment of Peri-implant Mucositis by Application of a Spermidine-based Gel

Peri-implant Mucositis Clinical Trial

Official title:
Treatment of Peri-implant Mucositis by Non-surgical Debridement and Additional Application of a Spermidine-based Gel

Clinical Trial Summary

The aim of the study is to evaluate the potential of a spermidine-based topical gel as an adjuvant to non-surgical treatment of peri-implant mucositis. After a meticulous selection, patients will be randomly assigned to Test (spermidine gel + non-surgical debridement) or Control group (non-surgical debridement).

Clinical Trial Description

Following the recording of the clinical parameters (BoP, FMPS, FMBS, PD), mechanical therapy (NSMD) will be performed in the Test group (spermidine gel) by means of an ultrasonic scaler with a plastic tip. Finally, the spermidine-based gel will be applied in the peri-implant sulcus using a blunt-tipped needle. Control group will instead be treated only through the NSMD. Finally, after 3 months the clinical parameters (BoP, FMPS, FMBS, PD) will be recorded again and the final evaluation will be performed. Data analysis will be performed using statistical software. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05926557
Study type Interventional
Source Federico II University
Contact Luca Ramaglia
Phone +393476912911
Email luca.ramaglia@unina.it
Status Recruiting
Phase N/A
Start date June 1, 2023
Completion date October 1, 2024
View Details
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