Risk Factors of Cat Scratch Colon Developing.

Mucosal Erosion Clinical Trial

— CSC  

Official title:

Risk Factors of Cat Scratch Colon Developing.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01574547
• Other study ID #: Dig-3
• Status: Completed
• Phase: N/A
• First received: April 8, 2012
• Last updated: April 9, 2012
• Start date: September 2007
• Est. completion date: April 2012

Study information

• Verified date: April 2012
• Source: University Hospital of the Nuestra Señora de Candelaria
• Contact: n/a
• Is FDA regulated: No
• Health authority: Spain: Comité Ético de Investigación Clínica
• Study type: Observational

Clinical Trial Summary

This study was designed to: estimate the incidence of cat scratch colon in the investigators environment; explore the diseases associated to its development; identify the factors related to its development; and assess its clinical repercussions.

Description:

All of the ambulatory colonoscopies performed at the investigators University Hospital from September 2007 were prospectively included in the study. Data recorded for each patient included: age, sex, disease background, reason for the examination, hematological data and the endoscopic diagnosis.

Every patient presenting CSC lesions had colon biopsies taken. These were studied by a single anatomic pathologist specializing in gastrointestinal pathologies.

The characteristics (age, sex, disease background, indication for surgery, age at the time of surgery, time elapsed since surgery, hematological data and pathoanatomical study of the colon biopsies) of diversion colitis patients with and without CSC lesions will bi compared.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 10715
• Est. completion date: April 2012
• Est. primary completion date: April 2012
• Accepts healthy volunteers: No
• Gender: Both
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• All of the ambulatory colonoscopies performed at our University Hospita

Exclusion Criteria:

• Patients thats refused.

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Mucosal Erosion

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital of the Nuestra Señora de Candelaria

References & Publications (12)

Baudet JS, Arguiñarena X, Díaz-Bethencourt D, Soler M, Avilés J. [Cat scratch colon. A little known condition]. Rev Esp Enferm Dig. 2008 Dec;100(12):790-1. Spanish. — View Citation

Baudet JS, Diaz-Bethencourt D, Arguiñarena X, Soler M, Morales S, Avilés J. Cat scratch colon is caused by barotrauma secondary to insufflation during colonoscopy. Endoscopy. 2008 Oct;40(10):878; author reply 878-9. doi: 10.1055/s-2008-1077562. Epub 2008 Sep 30. — View Citation

Cruz-Correa M, Milligan F, Giardiello FM, Bayless TM, Torbenson M, Yardley JH, Jackson FW, Wilson Jackson F. Collagenous colitis with mucosal tears on endoscopic insufflation: a unique presentation. Gut. 2002 Oct;51(4):600. — View Citation

Freeman HJ. Complications of collagenous colitis. World J Gastroenterol. 2008 Mar 21;14(11):1643-5. — View Citation

Hata K, Watanabe T, Kanazawa T, Kazama S, Shida D, Nagawa H. Mucosal tears on endoscopic insufflation. Gut. 2003 Apr;52(4):613; author reply 613. — View Citation

McDonnell WM, Loura F, Pointon MJ, Greenson JK. Cat scratch colon. Endoscopy. 2007 May;39(5):459-61. — View Citation

Mitchell JD, Teague R, Bolton R, Lowes J. Submucosal "dissection" in collagenous colitis. Gut. 2004 Mar;53(3):470. — View Citation

Purnak T, Ozaslan E, Yildiz A, Efe C. The cat scratch colon sign in a patient with chronic cholestasis. Endoscopy. 2010;42 Suppl 2:E117. doi: 10.1055/s-0029-1243983. Epub 2010 Mar 19. — View Citation

Sherman A, Ackert JJ, Rajapaksa R, West AB, Oweity T. Fractured colon: an endoscopically distinctive lesion associated with colonic perforation following colonoscopy in patients with collagenous colitis. J Clin Gastroenterol. 2004 Apr;38(4):341-5. — View Citation

van Velden R, Snieders I, Quispel R. Image of the month. Tearing of the colon in a patient with collagenous colitis during colonoscopy. Clin Gastroenterol Hepatol. 2010 Nov;8(11):A28. doi: 10.1016/j.cgh.2010.06.002. Epub 2010 Jun 25. — View Citation

Wickbom A, Lindqvist M, Bohr J, Ung KA, Bergman J, Eriksson S, Tysk C. Colonic mucosal tears in collagenous colitis. Scand J Gastroenterol. 2006 Jun;41(6):726-9. — View Citation

Yarze JC. Finding mucosal tears in collagenous colitis during colonoscopic insufflation. Gut. 2003 Apr;52(4):613-4; author reply 614. — View Citation

* Note: There are 12 references in all — Click here to view all references

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Presence of cat scratch colon during the endoscopy	Cat Scratch Colon: spontaneous tears appearing in the colon mucosa during colonoscopy	at the moment of colonoscopy	No