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Clinical Trial Summary

The purpose of this research study is to test the ability of Mucinex, an oral, over-the-counter, FDA approved expectorant) to stimulate the clearance of inhaled particles from the subject's lungs (called "mucociliary clearance"). The study will also monitor the metabolism of the drug by the subject's body.


Clinical Trial Description

n/a


Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT00902707
Study type Interventional
Source University of North Carolina, Chapel Hill
Contact
Status Completed
Phase Phase 1
Start date May 2009
Completion date May 2012

See also
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Completed NCT00999531 - A Randomized, Double-Blind, Placebo-Controlled Multiple Dose Trial of GS-9411 in Healthy Volunteers Phase 1
Completed NCT00325767 - Mucociliary Clearance in Healthy Subjects: Comparison of Levalbuterol and Racemic Albuterol Phase 4
Completed NCT05875025 - Study to Assess the Effect of the New HFA-152a Propellant on Mucociliary Clearance Phase 1
Recruiting NCT05755932 - Study to Assess Effect of HFO MDI Propellant on Mucociliary Clearance Compared to HFA MDI Propellant in Healthy Participants Phase 3
Withdrawn NCT01025713 - A Phase 1 Trial to Assess the Safety, Tolerability, and Pharmacokinetics of GS 9411 in Subjects With Cystic Fibrosis (CF) Phase 1