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Mucociliary Clearance clinical trials

View clinical trials related to Mucociliary Clearance.

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NCT ID: NCT05875025 Completed - Clinical trials for Mucociliary Clearance

Study to Assess the Effect of the New HFA-152a Propellant on Mucociliary Clearance

Start date: June 26, 2023
Phase: Phase 1
Study type: Interventional

The primary objective of this study is to assess the effect of multiple doses of the HFA-152a propellant and the HFA-134a propellant on mucociliary clearance (MCC).

NCT ID: NCT00999531 Completed - Cystic Fibrosis Clinical Trials

A Randomized, Double-Blind, Placebo-Controlled Multiple Dose Trial of GS-9411 in Healthy Volunteers

Start date: October 2009
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety and tolerability of repeated doses of GS-9411 in healthy volunteers. GS-9411 is a sodium channel inhibitor, that may restore airway hydration and mucociliary clearance in the lung.

NCT ID: NCT00951522 Completed - Cystic Fibrosis Clinical Trials

A Trial to Assess the Safety, Tolerability, and Pharmacokinetics of GS-9411 in Healthy Male Volunteers

Start date: September 2009
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety and tolerability of escalating doses of GS-9411 in healthy male volunteers. GS-9411 is a sodium channel inhibitor, that may restore airway hydration and mucociliary clearance in the lung.

NCT ID: NCT00902707 Completed - Clinical trials for Mucociliary Clearance

Evaluating the Effect of Mucinex® 1200 mg on Mucociliary and Cough Clearance From the Human Lung

Start date: May 2009
Phase: Phase 1
Study type: Interventional

The purpose of this research study is to test the ability of Mucinex, an oral, over-the-counter, FDA approved expectorant) to stimulate the clearance of inhaled particles from the subject's lungs (called "mucociliary clearance"). The study will also monitor the metabolism of the drug by the subject's body.

NCT ID: NCT00325767 Completed - Clinical trials for Mucociliary Clearance

Mucociliary Clearance in Healthy Subjects: Comparison of Levalbuterol and Racemic Albuterol

Start date: May 2004
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether lung mucociliary clearance (MCC) can be significantly enhanced in healthy subjects by one week of inhalation of nebulized levalbuterol aerosol, as compared to racemic albuterol or placebo. Subjects will inhale one week of levalbuterol, one week of racemic albuterol, and one week of placebo, in a randomized order.